Lipid phosphate phosphatase 3 in vascular pathophysiology

LPP3 is an integral membrane protein belonging to a family of enzymes (LPPs) that display broad substrate specificity and catalyse dephosphorylation of several lipid substrates, including lysophosphatidic acid and sphingosine-1-phosphate. In mammals, the LPP family consists of three enzymes named LP...

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Veröffentlicht in:	Atherosclerosis 2018-04, Vol.271, p.156-165
Hauptverfasser:	Busnelli, Marco, Manzini, Stefano, Parolini, Cinzia, Escalante-Alcalde, Diana, Chiesa, Giulia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Atherosclerosis Coronary artery disease Coronary Artery Disease - enzymology Coronary Artery Disease - genetics Coronary Artery Disease - physiopathology Coronary Vessels - enzymology Coronary Vessels - physiopathology Embryonic cardiovascular development Gene Expression Regulation, Developmental Genetic Predisposition to Disease Genome-wide association studies Humans Lipid phosphate phosphatase 3 Lysophosphatidic acid Phosphatidate Phosphatase - chemistry Phosphatidate Phosphatase - genetics Phosphatidate Phosphatase - metabolism Polymorphism, Genetic Protein Conformation Risk Factors Signal Transduction Sphingosine-1-phosphate Structure-Activity Relationship
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