The cytotoxic, apoptotic and oxidative effects of carbonic anhydrase IX inhibitor on colorectal cancer cells

Colorectal cancer (CRC) is the third most common tumor, malignant and has developed one of the main reasons of cancer mortality. According to studies conducted recently; carbonic anhydrase 9 (CAIX) is an especially attractive target for cancer therapy, in part since it is limited way expressed in no...

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Veröffentlicht in:	Journal of bioenergetics and biomembranes 2018-04, Vol.50 (2), p.107-116
Hauptverfasser:	Tülüce, Yasin, Ahmed, Bewar Ali, Koyuncu, İsmail, Durgun, Mustafa
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Animal Biochemistry Apoptosis Apoptosis - drug effects Biochemistry Bioorganic Chemistry Cancer Carbonic anhydrase Carbonic Anhydrase Inhibitors - pharmacology Carbonic Anhydrase Inhibitors - therapeutic use Carbonic anhydrases Cell cycle Cell Cycle Checkpoints - drug effects Cell Line, Tumor Cell Survival Chemistry Chemistry and Materials Science Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - drug therapy Colorectal Neoplasms - pathology Cytotoxicity Cytotoxins - pharmacology Cytotoxins - therapeutic use Flow cytometry Free radicals Histology Humans Inhibitors Morphology Organic Chemistry Oxidative stress Oxidative Stress - drug effects Reactive oxygen species Reactive Oxygen Species - metabolism Sulfonamides Sulfonamides - pharmacology Sulfonamides - therapeutic use Synthesis Toxicity
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