A germline-specific role for the mTORC2 component Rictor in maintaining spermatogonial differentiation and intercellular adhesion in mouse testis

What is the physiological role of Rictor in spermatogenic cells? Germline expression of Rictor regulates spermatogonial differentiation and has an essential role in coordinating germ cells and Sertoli cells in maintaining intact cell-cell adhesion dynamics and cytoskeleton-based architecture in the...

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Veröffentlicht in:	Molecular human reproduction 2018-05, Vol.24 (5), p.244-259
Hauptverfasser:	Bai, Shun, Cheng, Le, Zhang, Yingwen, Zhu, Chunsen, Zhu, Zhiping, Zhu, Ruping, Cheng, C Yan, Ye, Lan, Zheng, Ke
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood-Testis Barrier - cytology Blood-Testis Barrier - metabolism Cell Adhesion - physiology Germ Cells - cytology Germ Cells - metabolism Male Mice Rapamycin-Insensitive Companion of mTOR Protein - genetics Rapamycin-Insensitive Companion of mTOR Protein - metabolism Sertoli Cells - cytology Sertoli Cells - metabolism Spermatogenesis - physiology Spermatogonia - cytology Spermatogonia - metabolism Testis - cytology Testis - metabolism
Online-Zugang:	Volltext
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