Effects of AS2541019, a novel selective PI3Kδ inhibitor, on antibody production and hamster to rat xenotransplantation

B cell-mediated antibodies play a critical role in protecting the body from infections; however, excessive antibody production is involved in the pathogenesis of autoimmune diseases and transplanted organ rejection. Regulation of antibody production is therefore crucial for overcoming these complica...

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Veröffentlicht in:	European journal of pharmacology 2018-05, Vol.826, p.179-186
Hauptverfasser:	Marui, Takanori, Fukahori, Hidehiko, Kawashima, Tomoko, Ito, Misato, Akamatsu, Masahiko, Kaneko, Yoko, Takahashi, Fumie, Imada, Sunao, Morokata, Tatsuaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibody production B cell immunity PI3Kδ Xenotransplantation
Online-Zugang:	Volltext
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