The crux of Cux genes in neuronal function and plasticity

•Cut/Cux/CDP family of proteins belongs to the CUT class of homeobox genes.•Cux genes are expressed during neurogenesis and in specific neuronal subpopulations.•Perturbation of Cux expression is implicated in various diseases.•Expression of Cux1/2 in the cortex is restricted to neurons of the upper...

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Veröffentlicht in:	Brain research 2019-02, Vol.1705, p.32-42
Hauptverfasser:	Weiss, Linnea A., Nieto, Marta
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain disorders Cerebral Cortex - metabolism Cortex Cutl1 Cutl2 Cux1 Cux2 Embryonic Development Gene Expression Regulation, Developmental - genetics Hippocampus - metabolism Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Humans Neurogenesis - physiology Neuronal Plasticity - physiology Neurons - metabolism Nuclear Proteins - metabolism Pyramidal Cells - metabolism Repressor Proteins - genetics Repressor Proteins - metabolism Reprogramming Selector Superficial layers Transcription factors Transcription Factors - genetics Transcription Factors - metabolism Upper layers
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