A CRITICAL REVIEW ON PHARMACOLOGICAL SIGNIFICANCE OF HYDROGEN SULFIDE (H₂S) ON NF-κB CONCENTRATION AND ICAM-1 EXPRESSION IN RENAL ISCHEMIA REPERFUSION INJURY

Until recently hydrogen sulfide (H2S) was the least appreciated of the three gasotransmitters but now recognized as 3Y gaseous mediator after nitric oxide(NO) and carbon monoxide (CO). H2S regulates a number of physiological processes like vasorelaxation, prevention of inflammation, leukocyte adhesi...

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Veröffentlicht in:	Acta Poloniae pharmaceutica 2017-05, Vol.74 (3), p.747-752
Hauptverfasser:	Hashmp, Syed Fayaz, Sattar, Munavvar Z A, Rathore, Hassaan A, Ahmadi, Ashfaq, Johns, Edward J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Kidney Injury - drug therapy Acute Kidney Injury - metabolism Acute Kidney Injury - pathology Animals Humans Hydrogen Sulfide - therapeutic use Intercellular Adhesion Molecule-1 - metabolism Kidney - drug effects Kidney - metabolism Kidney - pathology Kidney Diseases - drug therapy Kidney Diseases - metabolism Kidney Diseases - pathology NF-kappa B - metabolism Reperfusion Injury - drug therapy Reperfusion Injury - metabolism Reperfusion Injury - pathology Signal Transduction - drug effects
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