Role of hyaluronan in atherosclerosis: Current knowledge and open questions

Hyaluronan (HA), HA synthases (HAS) and HA receptors are expressed during the progression of atherosclerotic plaques. HA is thought to promote the activated phenotype of local vascular smooth muscle cells characterized by increased migration, proliferation and matrix synthesis. Furthermore, HA may m...

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Veröffentlicht in:	Matrix biology 2019-05, Vol.78-79, p.324-336
1. Verfasser:	Fischer, Jens W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Arteriosclerosis Atherosclerosis Cell proliferation Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Glucose metabolism Hyaluronan Hyaluronic acid IL-1β Immune response Inflammation Interleukin-1β Leukocyte migration Lymphocytes T Macrophage Macrophages Myocardial infarction Phenotypes Plaques Smooth muscle T-cells Transcription
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