NEDD4L limits cAMP signaling through ubiquitination of CREB‐regulated transcription coactivator 3

The transcription factor cAMP‐responsive element‐binding protein (CREB) is involved in a variety of physiologic processes. Although its activity appears to be largely correlated with its phosphorylation status, cAMP‐mediated dephosphorylation and the subsequent nuclear migration of the CREB‐regulate...

Ausführliche Beschreibung