Reduced brain volumes in children of women with epilepsy: A neuropsychological and voxel based morphometric analysis in pre-adolescent children

•Mean FSIQ was lower in children with antenatal AED exposure (CAED) compared to controls (P=0.001)•CAED had also significantly reduced TBV,GMV (P

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Bibliographische Detailangaben
Veröffentlicht in:	Journal of neuroradiology 2018-10, Vol.45 (6), p.380-385
Hauptverfasser:	Sreedharan, R.M., Sheelakumari, R., Anila, K.M., Kesavadas, C., Thomas, S.V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticonvulsants - adverse effects Antiepileptic drugs Brain - drug effects Brain - pathology Child Children of woman with epilepsy Epilepsy - drug therapy Female Gray Matter - drug effects Gray Matter - pathology Grey matter volume Humans Male Neuropsychological Tests Pregnancy Prenatal Exposure Delayed Effects Total intracranial volume Voxel based morphometry White Matter - drug effects White Matter - pathology White matter volume
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Beschreibung
Zusammenfassung:	•Mean FSIQ was lower in children with antenatal AED exposure (CAED) compared to controls (P=0.001)•CAED had also significantly reduced TBV,GMV (P
ISSN:	0150-9861
DOI:	10.1016/j.neurad.2018.02.005