Endoscopic ultrasound guided brush/fine‐needle aspiration cytology: A 15‐month study
Background Endoscopic ultrasound‐guided fine‐needle aspiration (EUS‐FNA) has become increasingly popular for the diagnosis and staging of gastrointestinal diseases and peri‐gastrointestinal lesions. The application of FNA/Brush has dramatically expanded the clinical utility of EUS. Aims and objectiv...
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| Veröffentlicht in: | Diagnostic cytopathology 2018-06, Vol.46 (6), p.461-472 |
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| creator | Tummidi, Santosh Kothari, Kanchan Sathe, Pragati Agnihotri, Mona Fernandes, Gwendolyn Naik, Leena Jain, Aleena Chaturvedi, Rachana |
| description | Background
Endoscopic ultrasound‐guided fine‐needle aspiration (EUS‐FNA) has become increasingly popular for the diagnosis and staging of gastrointestinal diseases and peri‐gastrointestinal lesions. The application of FNA/Brush has dramatically expanded the clinical utility of EUS.
Aims and objective
To evaluate the diagnostic accuracy, study the spectrum of lesions encountered in EUS‐FNAC/brush cytology of gastrointestinal and peri‐gastrointestinal lesions.
Materials and methods
Total of 124 patients during the period from August 2015 to November 2016 was included in the study. Routine staining was done.
Results
A total of 124 cases were studied with 86% (107 cases) being satisfactory for evaluation. M:F ratio was 1:1.03, mean age of 50.5 years. The most common site was common bile duct (CBD) (37%) followed by lymph node (21%), pancreas (17.7%), esophagus (17%), stomach (3.5%), liver (1.8%), gallbladder (1%), and spleen (1%). In total, 53.4% lesions were benign, in 6.5% atypical cells were seen, 12.1% were suspicious for malignancy, and 28% cases were positive for malignancy. Follow‐up was available in 102 cases with cyto‐histopathological concordance rate of 90%.
Conclusion
EUS‐FNA/Brush is a reliable, sensitive, specific and minimally invasive way to establish a diagnosis. It can be utilized as a pre‐operative procedure for the management of many intra‐abdominal lesions and prevent unnecessary invasive procedures. |
| doi_str_mv | 10.1002/dc.23917 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2010841092</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2037310681</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3107-1ab1ca83fbb194bea703a9359867a7a1d41fbfb1a4423239d31cc8a55f6eb1433</originalsourceid><addsrcrecordid>eNp1kMtKxDAUhoMozngBn0AKbtzUyWnapnE3jOMFBtwouCu51enQNmPSIN35CD6jT2J0vIDg6mw-Pv7zIXQE-AwwTiZKniWEAd1CY8CMxpgQto3GBc2yGDBhI7Tn3ApjzBLId9EoYRlOE5qP0cO8U8ZJs65l5Jvecmd8p6JHXyutImG9W06qutNvL6-d1qrREXfr2vK-Nl0kh9405nE4j6YRZAFpTdcvI9d7NRygnYo3Th9-3X10fzm_m13Hi9urm9l0EUsCmMbABUhekEoIYKnQnGLCGclYkVNOOagUKlEJ4GmakPCjIiBlwbOsyrWAlJB9dLrxrq158tr1ZVs7qZuGd9p4VyYYcJGGKklAT_6gK-NtF9YFitCwJy_gVyitcc7qqlzbuuV2KAGXH7VLJcvP2gE9_hJ60Wr1A37nDUC8AZ7rRg__isqL2Ub4DiGPiRQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2037310681</pqid></control><display><type>article</type><title>Endoscopic ultrasound guided brush/fine‐needle aspiration cytology: A 15‐month study</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Tummidi, Santosh ; Kothari, Kanchan ; Sathe, Pragati ; Agnihotri, Mona ; Fernandes, Gwendolyn ; Naik, Leena ; Jain, Aleena ; Chaturvedi, Rachana</creator><creatorcontrib>Tummidi, Santosh ; Kothari, Kanchan ; Sathe, Pragati ; Agnihotri, Mona ; Fernandes, Gwendolyn ; Naik, Leena ; Jain, Aleena ; Chaturvedi, Rachana</creatorcontrib><description>Background
Endoscopic ultrasound‐guided fine‐needle aspiration (EUS‐FNA) has become increasingly popular for the diagnosis and staging of gastrointestinal diseases and peri‐gastrointestinal lesions. The application of FNA/Brush has dramatically expanded the clinical utility of EUS.
Aims and objective
To evaluate the diagnostic accuracy, study the spectrum of lesions encountered in EUS‐FNAC/brush cytology of gastrointestinal and peri‐gastrointestinal lesions.
Materials and methods
Total of 124 patients during the period from August 2015 to November 2016 was included in the study. Routine staining was done.
Results
A total of 124 cases were studied with 86% (107 cases) being satisfactory for evaluation. M:F ratio was 1:1.03, mean age of 50.5 years. The most common site was common bile duct (CBD) (37%) followed by lymph node (21%), pancreas (17.7%), esophagus (17%), stomach (3.5%), liver (1.8%), gallbladder (1%), and spleen (1%). In total, 53.4% lesions were benign, in 6.5% atypical cells were seen, 12.1% were suspicious for malignancy, and 28% cases were positive for malignancy. Follow‐up was available in 102 cases with cyto‐histopathological concordance rate of 90%.
Conclusion
EUS‐FNA/Brush is a reliable, sensitive, specific and minimally invasive way to establish a diagnosis. It can be utilized as a pre‐operative procedure for the management of many intra‐abdominal lesions and prevent unnecessary invasive procedures.</description><identifier>ISSN: 8755-1039</identifier><identifier>EISSN: 1097-0339</identifier><identifier>DOI: 10.1002/dc.23917</identifier><identifier>PMID: 29504276</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Bile ducts ; brush cytology ; Brushes ; common bile duct ; Cytology ; Diagnosis ; endoscopic guided ; Endoscopic Ultrasound-Guided Fine Needle Aspiration - methods ; Endoscopic Ultrasound-Guided Fine Needle Aspiration - standards ; Esophagus ; Female ; fine‐needle aspiration ; Gallbladder ; Gastrointestinal diseases ; Gastrointestinal Neoplasms - pathology ; gastrointestinal tract ; Humans ; Lesions ; Liver ; lymph node ; Lymph nodes ; Male ; Malignancy ; Middle Aged ; Pancreas ; Reproducibility of Results ; Sensitivity and Specificity ; Spleen ; Stomach</subject><ispartof>Diagnostic cytopathology, 2018-06, Vol.46 (6), p.461-472</ispartof><rights>2018 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3107-1ab1ca83fbb194bea703a9359867a7a1d41fbfb1a4423239d31cc8a55f6eb1433</cites><orcidid>0000-0002-3354-2637 ; 0000-0001-9048-259X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fdc.23917$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fdc.23917$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29504276$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tummidi, Santosh</creatorcontrib><creatorcontrib>Kothari, Kanchan</creatorcontrib><creatorcontrib>Sathe, Pragati</creatorcontrib><creatorcontrib>Agnihotri, Mona</creatorcontrib><creatorcontrib>Fernandes, Gwendolyn</creatorcontrib><creatorcontrib>Naik, Leena</creatorcontrib><creatorcontrib>Jain, Aleena</creatorcontrib><creatorcontrib>Chaturvedi, Rachana</creatorcontrib><title>Endoscopic ultrasound guided brush/fine‐needle aspiration cytology: A 15‐month study</title><title>Diagnostic cytopathology</title><addtitle>Diagn Cytopathol</addtitle><description>Background
Endoscopic ultrasound‐guided fine‐needle aspiration (EUS‐FNA) has become increasingly popular for the diagnosis and staging of gastrointestinal diseases and peri‐gastrointestinal lesions. The application of FNA/Brush has dramatically expanded the clinical utility of EUS.
Aims and objective
To evaluate the diagnostic accuracy, study the spectrum of lesions encountered in EUS‐FNAC/brush cytology of gastrointestinal and peri‐gastrointestinal lesions.
Materials and methods
Total of 124 patients during the period from August 2015 to November 2016 was included in the study. Routine staining was done.
Results
A total of 124 cases were studied with 86% (107 cases) being satisfactory for evaluation. M:F ratio was 1:1.03, mean age of 50.5 years. The most common site was common bile duct (CBD) (37%) followed by lymph node (21%), pancreas (17.7%), esophagus (17%), stomach (3.5%), liver (1.8%), gallbladder (1%), and spleen (1%). In total, 53.4% lesions were benign, in 6.5% atypical cells were seen, 12.1% were suspicious for malignancy, and 28% cases were positive for malignancy. Follow‐up was available in 102 cases with cyto‐histopathological concordance rate of 90%.
Conclusion
EUS‐FNA/Brush is a reliable, sensitive, specific and minimally invasive way to establish a diagnosis. It can be utilized as a pre‐operative procedure for the management of many intra‐abdominal lesions and prevent unnecessary invasive procedures.</description><subject>Bile ducts</subject><subject>brush cytology</subject><subject>Brushes</subject><subject>common bile duct</subject><subject>Cytology</subject><subject>Diagnosis</subject><subject>endoscopic guided</subject><subject>Endoscopic Ultrasound-Guided Fine Needle Aspiration - methods</subject><subject>Endoscopic Ultrasound-Guided Fine Needle Aspiration - standards</subject><subject>Esophagus</subject><subject>Female</subject><subject>fine‐needle aspiration</subject><subject>Gallbladder</subject><subject>Gastrointestinal diseases</subject><subject>Gastrointestinal Neoplasms - pathology</subject><subject>gastrointestinal tract</subject><subject>Humans</subject><subject>Lesions</subject><subject>Liver</subject><subject>lymph node</subject><subject>Lymph nodes</subject><subject>Male</subject><subject>Malignancy</subject><subject>Middle Aged</subject><subject>Pancreas</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Spleen</subject><subject>Stomach</subject><issn>8755-1039</issn><issn>1097-0339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kMtKxDAUhoMozngBn0AKbtzUyWnapnE3jOMFBtwouCu51enQNmPSIN35CD6jT2J0vIDg6mw-Pv7zIXQE-AwwTiZKniWEAd1CY8CMxpgQto3GBc2yGDBhI7Tn3ApjzBLId9EoYRlOE5qP0cO8U8ZJs65l5Jvecmd8p6JHXyutImG9W06qutNvL6-d1qrREXfr2vK-Nl0kh9405nE4j6YRZAFpTdcvI9d7NRygnYo3Th9-3X10fzm_m13Hi9urm9l0EUsCmMbABUhekEoIYKnQnGLCGclYkVNOOagUKlEJ4GmakPCjIiBlwbOsyrWAlJB9dLrxrq158tr1ZVs7qZuGd9p4VyYYcJGGKklAT_6gK-NtF9YFitCwJy_gVyitcc7qqlzbuuV2KAGXH7VLJcvP2gE9_hJ60Wr1A37nDUC8AZ7rRg__isqL2Ub4DiGPiRQ</recordid><startdate>201806</startdate><enddate>201806</enddate><creator>Tummidi, Santosh</creator><creator>Kothari, Kanchan</creator><creator>Sathe, Pragati</creator><creator>Agnihotri, Mona</creator><creator>Fernandes, Gwendolyn</creator><creator>Naik, Leena</creator><creator>Jain, Aleena</creator><creator>Chaturvedi, Rachana</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-3354-2637</orcidid><orcidid>https://orcid.org/0000-0001-9048-259X</orcidid></search><sort><creationdate>201806</creationdate><title>Endoscopic ultrasound guided brush/fine‐needle aspiration cytology: A 15‐month study</title><author>Tummidi, Santosh ; Kothari, Kanchan ; Sathe, Pragati ; Agnihotri, Mona ; Fernandes, Gwendolyn ; Naik, Leena ; Jain, Aleena ; Chaturvedi, Rachana</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3107-1ab1ca83fbb194bea703a9359867a7a1d41fbfb1a4423239d31cc8a55f6eb1433</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Bile ducts</topic><topic>brush cytology</topic><topic>Brushes</topic><topic>common bile duct</topic><topic>Cytology</topic><topic>Diagnosis</topic><topic>endoscopic guided</topic><topic>Endoscopic Ultrasound-Guided Fine Needle Aspiration - methods</topic><topic>Endoscopic Ultrasound-Guided Fine Needle Aspiration - standards</topic><topic>Esophagus</topic><topic>Female</topic><topic>fine‐needle aspiration</topic><topic>Gallbladder</topic><topic>Gastrointestinal diseases</topic><topic>Gastrointestinal Neoplasms - pathology</topic><topic>gastrointestinal tract</topic><topic>Humans</topic><topic>Lesions</topic><topic>Liver</topic><topic>lymph node</topic><topic>Lymph nodes</topic><topic>Male</topic><topic>Malignancy</topic><topic>Middle Aged</topic><topic>Pancreas</topic><topic>Reproducibility of Results</topic><topic>Sensitivity and Specificity</topic><topic>Spleen</topic><topic>Stomach</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tummidi, Santosh</creatorcontrib><creatorcontrib>Kothari, Kanchan</creatorcontrib><creatorcontrib>Sathe, Pragati</creatorcontrib><creatorcontrib>Agnihotri, Mona</creatorcontrib><creatorcontrib>Fernandes, Gwendolyn</creatorcontrib><creatorcontrib>Naik, Leena</creatorcontrib><creatorcontrib>Jain, Aleena</creatorcontrib><creatorcontrib>Chaturvedi, Rachana</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Diagnostic cytopathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tummidi, Santosh</au><au>Kothari, Kanchan</au><au>Sathe, Pragati</au><au>Agnihotri, Mona</au><au>Fernandes, Gwendolyn</au><au>Naik, Leena</au><au>Jain, Aleena</au><au>Chaturvedi, Rachana</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Endoscopic ultrasound guided brush/fine‐needle aspiration cytology: A 15‐month study</atitle><jtitle>Diagnostic cytopathology</jtitle><addtitle>Diagn Cytopathol</addtitle><date>2018-06</date><risdate>2018</risdate><volume>46</volume><issue>6</issue><spage>461</spage><epage>472</epage><pages>461-472</pages><issn>8755-1039</issn><eissn>1097-0339</eissn><abstract>Background
Endoscopic ultrasound‐guided fine‐needle aspiration (EUS‐FNA) has become increasingly popular for the diagnosis and staging of gastrointestinal diseases and peri‐gastrointestinal lesions. The application of FNA/Brush has dramatically expanded the clinical utility of EUS.
Aims and objective
To evaluate the diagnostic accuracy, study the spectrum of lesions encountered in EUS‐FNAC/brush cytology of gastrointestinal and peri‐gastrointestinal lesions.
Materials and methods
Total of 124 patients during the period from August 2015 to November 2016 was included in the study. Routine staining was done.
Results
A total of 124 cases were studied with 86% (107 cases) being satisfactory for evaluation. M:F ratio was 1:1.03, mean age of 50.5 years. The most common site was common bile duct (CBD) (37%) followed by lymph node (21%), pancreas (17.7%), esophagus (17%), stomach (3.5%), liver (1.8%), gallbladder (1%), and spleen (1%). In total, 53.4% lesions were benign, in 6.5% atypical cells were seen, 12.1% were suspicious for malignancy, and 28% cases were positive for malignancy. Follow‐up was available in 102 cases with cyto‐histopathological concordance rate of 90%.
Conclusion
EUS‐FNA/Brush is a reliable, sensitive, specific and minimally invasive way to establish a diagnosis. It can be utilized as a pre‐operative procedure for the management of many intra‐abdominal lesions and prevent unnecessary invasive procedures.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>29504276</pmid><doi>10.1002/dc.23917</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-3354-2637</orcidid><orcidid>https://orcid.org/0000-0001-9048-259X</orcidid></addata></record> |
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| identifier | ISSN: 8755-1039 |
| ispartof | Diagnostic cytopathology, 2018-06, Vol.46 (6), p.461-472 |
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| subjects | Bile ducts brush cytology Brushes common bile duct Cytology Diagnosis endoscopic guided Endoscopic Ultrasound-Guided Fine Needle Aspiration - methods Endoscopic Ultrasound-Guided Fine Needle Aspiration - standards Esophagus Female fine‐needle aspiration Gallbladder Gastrointestinal diseases Gastrointestinal Neoplasms - pathology gastrointestinal tract Humans Lesions Liver lymph node Lymph nodes Male Malignancy Middle Aged Pancreas Reproducibility of Results Sensitivity and Specificity Spleen Stomach |
| title | Endoscopic ultrasound guided brush/fine‐needle aspiration cytology: A 15‐month study |
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