Triptolide sensitizes breast cancer cells to Doxorubicin through the DNA damage response inhibition

Triptolide is an active component from a Chinese herb, Tripterygium wilfordii which has been applied for treating immune‐related diseases over centuries. Recently, it was reported that a variety of cancer cell lines could be sensitized to DNA‐damage based chemotherapy drugs in combination with Tript...

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Veröffentlicht in:	Molecular carcinogenesis 2018-06, Vol.57 (6), p.807-814
Hauptverfasser:	Deng, Yu, Li, Fulun, He, Pinglin, Yang, Yafei, Yang, Jin, Zhang, Yamei, Liu, Junying, Tong, Yongping, Li, Qingfeng, Mei, Xian, Shu, Zengyi, Zhao, Qi
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Fluorouracil Apoptosis ATM Breast cancer Cancer therapies Chemosensitization Chemotherapy Deoxyribonucleic acid DNA DNA damage DNA damage response Doxorubicin Immunosuppressive agents Mitomycin C Paclitaxel Triptolide Tumor cell lines
Online-Zugang:	Volltext
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