Population data and phylogenetic structure of Han population from Jiangsu province of China on GlobalFiler STR loci
Forensic statistical parameters based on allelic frequencies of commonly used short tandem repeats were estimated for the Han population of Jiangsu province from P.R. China. The 6-dye GlobalFiler™ PCR amplification kit incorporates 21 autosomal STRs, providing reliable DNA typing results with enhanc...
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| Veröffentlicht in: | International journal of legal medicine 2018-09, Vol.132 (5), p.1301-1304 |
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| creator | Adnan, Atif Zhan, Xiaoni Kasim, Kadirya Rakha, Allah Xin, Xing Jia |
| description | Forensic statistical parameters based on allelic frequencies of commonly used short tandem repeats were estimated for the Han population of Jiangsu province from P.R. China. The 6-dye GlobalFiler™ PCR amplification kit incorporates 21 autosomal STRs, providing reliable DNA typing results with enhanced the power of discrimination. Here, we analyzed the GlobalFiler™ STR loci in 516 unrelated individuals from Jiangsu Han population. A total of 256 alleles were observed ranging between 5 and 35.2 repeat units, and SE33 showed the greatest power of discrimination (34 alleles) in Jiangsu Han population. Most of the loci were found to be in the Hardy-Weinberg equilibrium after the Bonferroni correction with the exception of D3S1358. The combined power of exclusion (CPE) was 0.999999996353609, and the combined match probability (CMP) was 3.64 × 10
−25
. Phylogenetic parameters including pairwise genetic distances showed that Han population living in Jiangsu had closest genetic relationship with other East Asian populations. The present study provides precise reference database for forensic applications and population genetic studies. |
| doi_str_mv | 10.1007/s00414-018-1815-7 |
| format | Article |
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−25
. Phylogenetic parameters including pairwise genetic distances showed that Han population living in Jiangsu had closest genetic relationship with other East Asian populations. The present study provides precise reference database for forensic applications and population genetic studies.</description><identifier>ISSN: 0937-9827</identifier><identifier>EISSN: 1437-1596</identifier><identifier>DOI: 10.1007/s00414-018-1815-7</identifier><identifier>PMID: 29500610</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Deoxyribonucleic acid ; Discrimination ; DNA ; Forensic Medicine ; Gene loci ; Medical Law ; Medicine ; Medicine & Public Health ; Parameters ; Phylogenetics ; Population ; Population (statistical) ; Population Data ; Population genetics ; Statistical analysis</subject><ispartof>International journal of legal medicine, 2018-09, Vol.132 (5), p.1301-1304</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2018</rights><rights>International Journal of Legal Medicine is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-57338b3d6d2b7db73a7a512034ac43d89b1c51553ab80cd325116545a5470bc63</citedby><cites>FETCH-LOGICAL-c372t-57338b3d6d2b7db73a7a512034ac43d89b1c51553ab80cd325116545a5470bc63</cites><orcidid>0000-0003-4537-0059</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00414-018-1815-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00414-018-1815-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29500610$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Adnan, Atif</creatorcontrib><creatorcontrib>Zhan, Xiaoni</creatorcontrib><creatorcontrib>Kasim, Kadirya</creatorcontrib><creatorcontrib>Rakha, Allah</creatorcontrib><creatorcontrib>Xin, Xing Jia</creatorcontrib><title>Population data and phylogenetic structure of Han population from Jiangsu province of China on GlobalFiler STR loci</title><title>International journal of legal medicine</title><addtitle>Int J Legal Med</addtitle><addtitle>Int J Legal Med</addtitle><description>Forensic statistical parameters based on allelic frequencies of commonly used short tandem repeats were estimated for the Han population of Jiangsu province from P.R. China. The 6-dye GlobalFiler™ PCR amplification kit incorporates 21 autosomal STRs, providing reliable DNA typing results with enhanced the power of discrimination. Here, we analyzed the GlobalFiler™ STR loci in 516 unrelated individuals from Jiangsu Han population. A total of 256 alleles were observed ranging between 5 and 35.2 repeat units, and SE33 showed the greatest power of discrimination (34 alleles) in Jiangsu Han population. Most of the loci were found to be in the Hardy-Weinberg equilibrium after the Bonferroni correction with the exception of D3S1358. The combined power of exclusion (CPE) was 0.999999996353609, and the combined match probability (CMP) was 3.64 × 10
−25
. Phylogenetic parameters including pairwise genetic distances showed that Han population living in Jiangsu had closest genetic relationship with other East Asian populations. The present study provides precise reference database for forensic applications and population genetic studies.</description><subject>Deoxyribonucleic acid</subject><subject>Discrimination</subject><subject>DNA</subject><subject>Forensic Medicine</subject><subject>Gene loci</subject><subject>Medical Law</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Parameters</subject><subject>Phylogenetics</subject><subject>Population</subject><subject>Population (statistical)</subject><subject>Population Data</subject><subject>Population genetics</subject><subject>Statistical analysis</subject><issn>0937-9827</issn><issn>1437-1596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp1kU9r3DAQxUVISbZJPkAuQZBLLm5nLMuyj2Fpsi0LLU1yFrKs3VXQSo5kF_bbR-nmDxR6moH5vTfDPELOEb4ggPiaACqsCsCmwAZ5IQ7IDCsmCuRtfUhm0Oa-bUpxTD6n9AiAohb8iByXLQeoEWYk_QrD5NRog6e9GhVVvqfDZufC2ngzWk3TGCc9TtHQsKIL5enwoVjFsKU_rPLrNNEhhj_W67_cfGO9opm4daFT7sY6E-nd_W_qgran5NNKuWTOXusJebj5dj9fFMuft9_n18tCM1GOBReMNR3r677sRN8JpoTiWAKrlK5Y37Qdao6cM9U1oHtWcsSaV1zxSkCna3ZCrva--bKnyaRRbm3SxjnlTZiSLAEhbwKBGb38B30MU_T5ukxBm9-Wn5wp3FM6hpSiWckh2q2KO4kgXxKR-0RkhuVLIlJkzcWr89RtTf-ueIsgA-UeSHnk1yZ-rP6_6zPXWpVO</recordid><startdate>20180901</startdate><enddate>20180901</enddate><creator>Adnan, Atif</creator><creator>Zhan, Xiaoni</creator><creator>Kasim, Kadirya</creator><creator>Rakha, Allah</creator><creator>Xin, Xing Jia</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AM</scope><scope>8AO</scope><scope>8FE</scope><scope>8FG</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BGRYB</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>HCIFZ</scope><scope>K7.</scope><scope>K9.</scope><scope>L6V</scope><scope>M0O</scope><scope>M0S</scope><scope>M1P</scope><scope>M7S</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRQQA</scope><scope>PTHSS</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4537-0059</orcidid></search><sort><creationdate>20180901</creationdate><title>Population data and phylogenetic structure of Han population from Jiangsu province of China on GlobalFiler STR loci</title><author>Adnan, Atif ; 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China. The 6-dye GlobalFiler™ PCR amplification kit incorporates 21 autosomal STRs, providing reliable DNA typing results with enhanced the power of discrimination. Here, we analyzed the GlobalFiler™ STR loci in 516 unrelated individuals from Jiangsu Han population. A total of 256 alleles were observed ranging between 5 and 35.2 repeat units, and SE33 showed the greatest power of discrimination (34 alleles) in Jiangsu Han population. Most of the loci were found to be in the Hardy-Weinberg equilibrium after the Bonferroni correction with the exception of D3S1358. The combined power of exclusion (CPE) was 0.999999996353609, and the combined match probability (CMP) was 3.64 × 10
−25
. Phylogenetic parameters including pairwise genetic distances showed that Han population living in Jiangsu had closest genetic relationship with other East Asian populations. The present study provides precise reference database for forensic applications and population genetic studies.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>29500610</pmid><doi>10.1007/s00414-018-1815-7</doi><tpages>4</tpages><orcidid>https://orcid.org/0000-0003-4537-0059</orcidid></addata></record> |
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| subjects | Deoxyribonucleic acid Discrimination DNA Forensic Medicine Gene loci Medical Law Medicine Medicine & Public Health Parameters Phylogenetics Population Population (statistical) Population Data Population genetics Statistical analysis |
| title | Population data and phylogenetic structure of Han population from Jiangsu province of China on GlobalFiler STR loci |
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