Coronary heart disease, heart failure, and the risk of dementia: A systematic review and meta-analysis
Cardiovascular risk factors are closely linked with dementia risk, but whether heart disease predisposes to dementia is uncertain. We systematically reviewed the literature and meta-analyzed risk estimates from longitudinal studies reporting the association of coronary heart disease (CHD) or heart f...
Gespeichert in:
| Veröffentlicht in: | Alzheimer's & dementia 2018-11, Vol.14 (11), p.1493-1504 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1504 |
|---|---|
| container_issue | 11 |
| container_start_page | 1493 |
| container_title | Alzheimer's & dementia |
| container_volume | 14 |
| creator | Wolters, Frank J. Segufa, Reffat A. Darweesh, Sirwan K.L. Bos, Daniel Ikram, Mohammad Arfan Sabayan, Behnam Hofman, Albert Sedaghat, Sanaz |
| description | Cardiovascular risk factors are closely linked with dementia risk, but whether heart disease predisposes to dementia is uncertain.
We systematically reviewed the literature and meta-analyzed risk estimates from longitudinal studies reporting the association of coronary heart disease (CHD) or heart failure (HF) with risk of dementia.
We identified 16 studies (1,309,483 individuals) regarding CHD, and seven studies (1,958,702 individuals) about HF. A history of CHD was associated with a 27% increased risk of dementia (pooled relative risk [RR] [95% confidence interval, CI]: 1.27 [1.07–1.50]), albeit with considerable heterogeneity across studies (I2 = 80%). HF was associated with 60% increased dementia risk (pooled RR 1.60 [1.19–2.13]) with moderate heterogeneity (I2 = 59%). Among prospective population-based cohorts, pooled estimates were similar (for CHD, RR 1.26 [1.06–1.49], nine studies; and HF, RR 1.80 [1.41–2.31], four studies) and highly consistent (I2 = 0%).
CHD and HF are associated with an increased risk of dementia. |
| doi_str_mv | 10.1016/j.jalz.2018.01.007 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2010366940</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1552526018300268</els_id><sourcerecordid>2010366940</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4807-f7493b0bb2c9c6212d1a771609f4ca64026e6cdff68d6e391bf2c35329b39fe83</originalsourceid><addsrcrecordid>eNqNkDtv2zAUhYkiQfNo_0CHgmOGSrmkJEosuhhGmzYwkCVZuhAUeQnT0SMl5QTOry8dOx6DLCQvcc65Bx8hXxjkDJi4XOUr3T3nHFiTA8sB6g_klFUVzypey6PDW8AJOYtxBVBCw6qP5ITLUpYNNKfEzccwDjps6BJ1mKj1EXXEb_vRad-tQxr1YOm0RBp8vKejoxZ7HCavv9MZjZs4Ya8nb2jAR49PL-oeJ53pQXeb6OMncux0F_Hz_j4nd79-3s5_Z4ubqz_z2SIzqU6dubqURQtty400gjNuma5rJkC60mhRAhcojHVONFZgIVnruCmqgsu2kA6b4pxc7HIfwvhvjXFSvY8Gu04POK6jSqygEEKWkKR8JzVhjDGgUw_B94mEYqC2fNVKbfluPY0CphLfZPq6z1-3PdqD5RVoEsx2giff4eYdkWq2-Ht9nY7tX2r3suTHLgMTqcQzqGg8DgatD2gmZUf_Vsf_iCOf0g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2010366940</pqid></control><display><type>article</type><title>Coronary heart disease, heart failure, and the risk of dementia: A systematic review and meta-analysis</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Wolters, Frank J. ; Segufa, Reffat A. ; Darweesh, Sirwan K.L. ; Bos, Daniel ; Ikram, Mohammad Arfan ; Sabayan, Behnam ; Hofman, Albert ; Sedaghat, Sanaz</creator><creatorcontrib>Wolters, Frank J. ; Segufa, Reffat A. ; Darweesh, Sirwan K.L. ; Bos, Daniel ; Ikram, Mohammad Arfan ; Sabayan, Behnam ; Hofman, Albert ; Sedaghat, Sanaz</creatorcontrib><description>Cardiovascular risk factors are closely linked with dementia risk, but whether heart disease predisposes to dementia is uncertain.
We systematically reviewed the literature and meta-analyzed risk estimates from longitudinal studies reporting the association of coronary heart disease (CHD) or heart failure (HF) with risk of dementia.
We identified 16 studies (1,309,483 individuals) regarding CHD, and seven studies (1,958,702 individuals) about HF. A history of CHD was associated with a 27% increased risk of dementia (pooled relative risk [RR] [95% confidence interval, CI]: 1.27 [1.07–1.50]), albeit with considerable heterogeneity across studies (I2 = 80%). HF was associated with 60% increased dementia risk (pooled RR 1.60 [1.19–2.13]) with moderate heterogeneity (I2 = 59%). Among prospective population-based cohorts, pooled estimates were similar (for CHD, RR 1.26 [1.06–1.49], nine studies; and HF, RR 1.80 [1.41–2.31], four studies) and highly consistent (I2 = 0%).
CHD and HF are associated with an increased risk of dementia.</description><identifier>ISSN: 1552-5260</identifier><identifier>EISSN: 1552-5279</identifier><identifier>DOI: 10.1016/j.jalz.2018.01.007</identifier><identifier>PMID: 29494808</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Alzheimer's disease ; Coronary heart disease ; Dementia ; Heart failure ; Myocardial infarction</subject><ispartof>Alzheimer's & dementia, 2018-11, Vol.14 (11), p.1493-1504</ispartof><rights>2018 the Alzheimer's Association</rights><rights>2018 The Alzheimer's Association</rights><rights>Copyright © 2018 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4807-f7493b0bb2c9c6212d1a771609f4ca64026e6cdff68d6e391bf2c35329b39fe83</citedby><cites>FETCH-LOGICAL-c4807-f7493b0bb2c9c6212d1a771609f4ca64026e6cdff68d6e391bf2c35329b39fe83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1016%2Fj.jalz.2018.01.007$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1016%2Fj.jalz.2018.01.007$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29494808$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wolters, Frank J.</creatorcontrib><creatorcontrib>Segufa, Reffat A.</creatorcontrib><creatorcontrib>Darweesh, Sirwan K.L.</creatorcontrib><creatorcontrib>Bos, Daniel</creatorcontrib><creatorcontrib>Ikram, Mohammad Arfan</creatorcontrib><creatorcontrib>Sabayan, Behnam</creatorcontrib><creatorcontrib>Hofman, Albert</creatorcontrib><creatorcontrib>Sedaghat, Sanaz</creatorcontrib><title>Coronary heart disease, heart failure, and the risk of dementia: A systematic review and meta-analysis</title><title>Alzheimer's & dementia</title><addtitle>Alzheimers Dement</addtitle><description>Cardiovascular risk factors are closely linked with dementia risk, but whether heart disease predisposes to dementia is uncertain.
We systematically reviewed the literature and meta-analyzed risk estimates from longitudinal studies reporting the association of coronary heart disease (CHD) or heart failure (HF) with risk of dementia.
We identified 16 studies (1,309,483 individuals) regarding CHD, and seven studies (1,958,702 individuals) about HF. A history of CHD was associated with a 27% increased risk of dementia (pooled relative risk [RR] [95% confidence interval, CI]: 1.27 [1.07–1.50]), albeit with considerable heterogeneity across studies (I2 = 80%). HF was associated with 60% increased dementia risk (pooled RR 1.60 [1.19–2.13]) with moderate heterogeneity (I2 = 59%). Among prospective population-based cohorts, pooled estimates were similar (for CHD, RR 1.26 [1.06–1.49], nine studies; and HF, RR 1.80 [1.41–2.31], four studies) and highly consistent (I2 = 0%).
CHD and HF are associated with an increased risk of dementia.</description><subject>Alzheimer's disease</subject><subject>Coronary heart disease</subject><subject>Dementia</subject><subject>Heart failure</subject><subject>Myocardial infarction</subject><issn>1552-5260</issn><issn>1552-5279</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNqNkDtv2zAUhYkiQfNo_0CHgmOGSrmkJEosuhhGmzYwkCVZuhAUeQnT0SMl5QTOry8dOx6DLCQvcc65Bx8hXxjkDJi4XOUr3T3nHFiTA8sB6g_klFUVzypey6PDW8AJOYtxBVBCw6qP5ITLUpYNNKfEzccwDjps6BJ1mKj1EXXEb_vRad-tQxr1YOm0RBp8vKejoxZ7HCavv9MZjZs4Ya8nb2jAR49PL-oeJ53pQXeb6OMncux0F_Hz_j4nd79-3s5_Z4ubqz_z2SIzqU6dubqURQtty400gjNuma5rJkC60mhRAhcojHVONFZgIVnruCmqgsu2kA6b4pxc7HIfwvhvjXFSvY8Gu04POK6jSqygEEKWkKR8JzVhjDGgUw_B94mEYqC2fNVKbfluPY0CphLfZPq6z1-3PdqD5RVoEsx2giff4eYdkWq2-Ht9nY7tX2r3suTHLgMTqcQzqGg8DgatD2gmZUf_Vsf_iCOf0g</recordid><startdate>201811</startdate><enddate>201811</enddate><creator>Wolters, Frank J.</creator><creator>Segufa, Reffat A.</creator><creator>Darweesh, Sirwan K.L.</creator><creator>Bos, Daniel</creator><creator>Ikram, Mohammad Arfan</creator><creator>Sabayan, Behnam</creator><creator>Hofman, Albert</creator><creator>Sedaghat, Sanaz</creator><general>Elsevier Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201811</creationdate><title>Coronary heart disease, heart failure, and the risk of dementia: A systematic review and meta-analysis</title><author>Wolters, Frank J. ; Segufa, Reffat A. ; Darweesh, Sirwan K.L. ; Bos, Daniel ; Ikram, Mohammad Arfan ; Sabayan, Behnam ; Hofman, Albert ; Sedaghat, Sanaz</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4807-f7493b0bb2c9c6212d1a771609f4ca64026e6cdff68d6e391bf2c35329b39fe83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Alzheimer's disease</topic><topic>Coronary heart disease</topic><topic>Dementia</topic><topic>Heart failure</topic><topic>Myocardial infarction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wolters, Frank J.</creatorcontrib><creatorcontrib>Segufa, Reffat A.</creatorcontrib><creatorcontrib>Darweesh, Sirwan K.L.</creatorcontrib><creatorcontrib>Bos, Daniel</creatorcontrib><creatorcontrib>Ikram, Mohammad Arfan</creatorcontrib><creatorcontrib>Sabayan, Behnam</creatorcontrib><creatorcontrib>Hofman, Albert</creatorcontrib><creatorcontrib>Sedaghat, Sanaz</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Alzheimer's & dementia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wolters, Frank J.</au><au>Segufa, Reffat A.</au><au>Darweesh, Sirwan K.L.</au><au>Bos, Daniel</au><au>Ikram, Mohammad Arfan</au><au>Sabayan, Behnam</au><au>Hofman, Albert</au><au>Sedaghat, Sanaz</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Coronary heart disease, heart failure, and the risk of dementia: A systematic review and meta-analysis</atitle><jtitle>Alzheimer's & dementia</jtitle><addtitle>Alzheimers Dement</addtitle><date>2018-11</date><risdate>2018</risdate><volume>14</volume><issue>11</issue><spage>1493</spage><epage>1504</epage><pages>1493-1504</pages><issn>1552-5260</issn><eissn>1552-5279</eissn><abstract>Cardiovascular risk factors are closely linked with dementia risk, but whether heart disease predisposes to dementia is uncertain.
We systematically reviewed the literature and meta-analyzed risk estimates from longitudinal studies reporting the association of coronary heart disease (CHD) or heart failure (HF) with risk of dementia.
We identified 16 studies (1,309,483 individuals) regarding CHD, and seven studies (1,958,702 individuals) about HF. A history of CHD was associated with a 27% increased risk of dementia (pooled relative risk [RR] [95% confidence interval, CI]: 1.27 [1.07–1.50]), albeit with considerable heterogeneity across studies (I2 = 80%). HF was associated with 60% increased dementia risk (pooled RR 1.60 [1.19–2.13]) with moderate heterogeneity (I2 = 59%). Among prospective population-based cohorts, pooled estimates were similar (for CHD, RR 1.26 [1.06–1.49], nine studies; and HF, RR 1.80 [1.41–2.31], four studies) and highly consistent (I2 = 0%).
CHD and HF are associated with an increased risk of dementia.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>29494808</pmid><doi>10.1016/j.jalz.2018.01.007</doi><tpages>12</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1552-5260 |
| ispartof | Alzheimer's & dementia, 2018-11, Vol.14 (11), p.1493-1504 |
| issn | 1552-5260 1552-5279 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2010366940 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Alzheimer's disease Coronary heart disease Dementia Heart failure Myocardial infarction |
| title | Coronary heart disease, heart failure, and the risk of dementia: A systematic review and meta-analysis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T13%3A51%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Coronary%20heart%20disease,%20heart%20failure,%20and%20the%20risk%20of%20dementia:%20A%20systematic%20review%20and%20meta-analysis&rft.jtitle=Alzheimer's%20&%20dementia&rft.au=Wolters,%20Frank%20J.&rft.date=2018-11&rft.volume=14&rft.issue=11&rft.spage=1493&rft.epage=1504&rft.pages=1493-1504&rft.issn=1552-5260&rft.eissn=1552-5279&rft_id=info:doi/10.1016/j.jalz.2018.01.007&rft_dat=%3Cproquest_cross%3E2010366940%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2010366940&rft_id=info:pmid/29494808&rft_els_id=S1552526018300268&rfr_iscdi=true |