Exploiting Nanobodies' Singular Traits

The unique class of heavy chain-only antibodies, present in Camelidae, can be shrunk to just the variable region of the heavy chain to yield VHHs, also called nanobodies. About one-tenth the size of their full-size counterparts, nanobodies can serve in applications similar to those for conventional...

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Veröffentlicht in:	Annual review of immunology 2018-04, Vol.36 (1), p.695-715
Hauptverfasser:	Ingram, Jessica R, Schmidt, Florian I, Ploegh, Hidde L
Format:	Artikel
Sprache:	eng
Schlagworte:	camelids crystallization nanobodies phage display phenotypic screen
Online-Zugang:	Volltext
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