E-cadherin mediated lateral interactions between neighbor cells necessary for collective migration

Collective cell movement is critical in pathological processes such as wound healing and cancer invasion. It entails complex interactions between adjacent cells and between cells-extracellular matrices. Most studies measure the migration patterns and force propagation by placing cells on flat, patte...

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Veröffentlicht in:	Journal of biomechanics 2018-04, Vol.71, p.159-166
Hauptverfasser:	Suffoletto, Kevin, Jetta, Deekshitha, Hua, Susan Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinin adherens junction (AJ) Adhesion tests Adhesives Cancer Cell adhesion & migration Cell culture Cell interactions Cell migration Cell-cell contact Channels Coatings Crosslinking Cytoskeletal forces E-cadherin Epithelial cells Fluorescence resonance energy transfer Intercellular adhesion Kinases Microfluidic channel Microfluidics Proteins Shear stress Substrates Wound healing
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