Retroviral-Based BMP-4 In Vivo Gene Transfer Strategy with Intramedullary Viral Delivery Optimizes Transgene Expression in Rat Femur Fractures

We have developed an intramedullary delivery strategy to administer retroviral vectors expressing a therapeutic gene to promote healing of a closed rat femur fracture. This strategy involves implantation of an indwelling catheter with the stabilizing Kirschner (K)-wire during the surgery prior to fr...

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Veröffentlicht in:	The open tissue engineering and regenerative medicine journal 2008-11, Vol.1 (1), p.14-22
Hauptverfasser:	Rundle, Charles H., Chen, Shin-Tai, Porte, Ryan, Wergedal, Jon E., Lau, K.-H. William
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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