Identification of an Immortalized Human Airway Epithelial Cell Line with Dyskinetic Cilia

Primary ciliary dyskinesia is an inherited, currently incurable condition. In the respiratory system, primary ciliary dyskinesia causes impaired functioning of the mucociliary escalator, leading to nasal congestion, cough, and recurrent otitis media, and commonly progresses to cause more serious and...

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Veröffentlicht in:	American journal of respiratory cell and molecular biology 2018-09, Vol.59 (3), p.375-382
Hauptverfasser:	Kuek, Li Eon, Griffin, Paul, Martinello, Paul, Graham, Alison N, Kalitsis, Paul, Robinson, Philip J, Mackay, Graham A
Format:	Artikel
Sprache:	eng
Schlagworte:	Bronchiectasis Cell Differentiation - physiology Cell Line Cells, Cultured Cilia Cilia - pathology Ciliary Motility Disorders - pathology Cough Dyskinesias - pathology Ear diseases Electron microscopy Epithelial cells Epithelial Cells - cytology Genes Humans Microscopy Mutation Otitis media Primary ciliary dyskinesia Respiratory system Respiratory tract Sinusitis Transposition
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