Protracted cannabinoid administration elicits antidepressant behavioral responses in rats: Role of gender and noradrenergic transmission

Abstract Research has shown that enhancement of cannabinoid CB1 receptor activity elicits an antidepressant-like response in the forced swim test (FST); however, the effects of chronic administration of cannabinoid agents in the FST are not well characterized. In Experiment 1, the CB1 receptor agoni...

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Veröffentlicht in:	Physiology & behavior 2009-08, Vol.98 (1), p.118-124
Hauptverfasser:	Morrish, Anna C, Hill, Matthew N, Riebe, Caitlin J.N, Gorzalka, Boris B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Antagonists - pharmacology Adrenergic beta-Antagonists - pharmacology Adult and adolescent clinical studies Animals Antidepressant Antidepressive Agents Antidepressive Agents, Tricyclic - pharmacology Behavior, Animal - drug effects Behavioral psychophysiology Biological and medical sciences Cannabinoids - administration & dosage Cannabinoids - antagonists & inhibitors Cannabinoids - pharmacology Cannabis Depression Desipramine - pharmacology Dronabinol - analogs & derivatives Dronabinol - pharmacology Female Fundamental and applied biological sciences. Psychology Male Medical sciences Mood disorders Neuropharmacology Norepinephrine Norepinephrine - physiology Pharmacology. Drug treatments Piperidines - pharmacology Prazosin - pharmacology Propranolol - pharmacology Psychiatry Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Psychopathology. Psychiatry Psychopharmacology Pyrazoles - pharmacology Rats Rats, Sprague-Dawley Receptor, Cannabinoid, CB1 - agonists Sex Characteristics Substance Withdrawal Syndrome - psychology Swimming - psychology Synaptic Transmission - drug effects Withdrawal
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