Embelin and its derivatives unravel the signaling, proinflammatory and antiatherogenic properties of GPR84 receptor

[Display omitted] GPR84 is an orphan G-protein coupled receptor, expressed on monocytes, macrophages and neutrophils and is significantly upregulated by inflammatory stimuli. The physiological role of GPR84 remains largely unknown. Medium chain fatty acids (MCFA) activate the receptor and have been...

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Veröffentlicht in:	Pharmacological research 2018-05, Vol.131, p.185-198
Hauptverfasser:	Gaidarov, Ibragim, Anthony, Todd, Gatlin, Joel, Chen, Xiaohua, Mills, David, Solomon, Michelle, Han, Sangdon, Semple, Graeme, Unett, David J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Atherosclerosis Cholesterol efflux Embelin GPR84 Macrophage Neutrophil
Online-Zugang:	Volltext
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