Biogenesis and function of extracellular vesicles in cancer

Extracellular vesicles (EVs) are heterogeneous multi-signal messengers that support cancer growth and dissemination by mediating the tumor-stroma crosstalk. Exosomes are a subtype of EVs that originate from the limiting membrane of late endosomes, and as such contain information linked to both the i...

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Veröffentlicht in:	Pharmacology & therapeutics (Oxford) 2018-08, Vol.188, p.1-11
Hauptverfasser:	Bebelman, Maarten P., Smit, Martine J., Pegtel, D. Michiel, Baglio, S. Rubina
Format:	Artikel
Sprache:	eng
Schlagworte:	Cargo sorting Exosome biogenesis Extracellular vesicles Tumor microenvironment Tumor-stroma communication
Online-Zugang:	Volltext
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