Index Case of Cutaneous Follicular Mycosis Fungoides With Central Nervous System Involvement and Review of Literature
Central nervous system involvement by mycosis fungoides (MF) is rare and is usually seen in advanced stages of the disease. We describe a patient with early-stage follicular MF who presented with changes in mental status. Despite an initial diagnosis of vasculitis based on clinical and brain biopsy...
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| Veröffentlicht in: | The American journal of dermatopathology 2018-03, Vol.40 (3), p.185-190 |
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| container_end_page | 190 |
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| container_title | The American journal of dermatopathology |
| container_volume | 40 |
| creator | Nguyen, Giang Huong Mohler, Alexander Leppert, Michelle Parra, Cindy Zeng, Yue-Ping Prok, Lori Schowinsky, Jeffrey Magro, Cynthia M Pacheco, Theresa Ney, Douglas |
| description | Central nervous system involvement by mycosis fungoides (MF) is rare and is usually seen in advanced stages of the disease. We describe a patient with early-stage follicular MF who presented with changes in mental status. Despite an initial diagnosis of vasculitis based on clinical and brain biopsy results, the postmortem examination revealed extensive infiltration of MF cells throughout the brain with leptomeningeal involvement. This case in addition to the accompanied review of literature illustrates the importance of the awareness of central nervous system involvement by MF and highlights the need for an urgent neurologic evaluation in patients with a history of MF now presenting with neurologic signs or symptoms. |
| doi_str_mv | 10.1097/DAD.0000000000000955 |
| format | Article |
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| identifier | ISSN: 0193-1091 |
| ispartof | The American journal of dermatopathology, 2018-03, Vol.40 (3), p.185-190 |
| issn | 0193-1091 1533-0311 |
| language | eng |
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| source | MEDLINE; Journals@Ovid Ovid Autoload |
| subjects | Brain Neoplasms - pathology Fatal Outcome Humans Male Middle Aged Mycosis Fungoides - pathology Skin Neoplasms - pathology |
| title | Index Case of Cutaneous Follicular Mycosis Fungoides With Central Nervous System Involvement and Review of Literature |
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