Clinical Notes: Donepezil Treatment of Topiramate-Related Cognitive Dysfunction
Six migraine patients experienced significant topiramate-related cognitive and language dysfunction that improved with donepezil treatment and allowed uninterrupted topiramate use. These patients represent the first report of topiramate-related cognitive and language dysfunction that improved with a...
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Veröffentlicht in: | Headache 2006-02, Vol.46 (2), p.332-335 |
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description | Six migraine patients experienced significant topiramate-related cognitive and language dysfunction that improved with donepezil treatment and allowed uninterrupted topiramate use. These patients represent the first report of topiramate-related cognitive and language dysfunction that improved with a cholinesterase inhibitor. Although, the mechanism responsible for this effect is uncertain, cholinesterase inhibition resulting in cholinergic augmentation and enhanced cognition probably account for some if not most of the improvement. |
doi_str_mv | 10.1111/j.1526-4610.2006.00348_1.x |
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title | Clinical Notes: Donepezil Treatment of Topiramate-Related Cognitive Dysfunction |
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