Quantitative Analysis of Glucose Metabolic Cleavage in Glucose Transporters Overexpressed Cancer Cells by Target-Specific Fluorescent Gold Nanoclusters

The glucose metabolism rate in cancer cells is a crucial piece of information for the cancer aggressiveness. A feasible method to monitor processes of oncogenic mutations has been demonstrated in this work. The fluorescent gold nanoclusters conjugated with glucose (glucose-AuNCs) were successfully s...

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Veröffentlicht in:	Analytical chemistry (Washington) 2018-03, Vol.90 (6), p.3974-3980
Hauptverfasser:	Cheng, Tsai-Mu, Chu, Hsueh-Liang, Lee, Yi-Cheng, Wang, Di-Yan, Chang, Che-Chang, Chung, Kuan-Lan, Yen, Hung-Chi, Hsiao, Chu-Wen, Pan, Xi-Yu, Kuo, Tsung-Rong, Chen, Chia-Chun
Format:	Artikel
Sprache:	eng
Schlagworte:	ABC transporters Biocompatibility Biomedical materials Biosensing Techniques - methods Cancer Cell Line, Tumor Chemistry Cleavage Cluster analysis Enzymes Fluorescent Dyes - chemistry Fluorescent indicators Fourier transforms Glucose Glucose - chemistry Glucose - metabolism Glucose Transport Proteins, Facilitative - analysis Glucose Transport Proteins, Facilitative - metabolism Glycolysis Gold Gold - chemistry Humans Metabolism Metal Nanoparticles - chemistry Microscopy, Confocal - methods Microscopy, Fluorescence - methods Mutation Nanoclusters Neoplasms - enzymology Neoplasms - metabolism Quantitative analysis Reaction kinetics Reaction time
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