Temperature-Induced Surface Effects on Drug Nanosuspensions

ABSTRACT Purpose The trial-and-error approach is still predominantly used in pharmaceutical development of nanosuspensions. Physicochemical dispersion stability is a primary focus and therefore, various analytical bulk methods are commonly employed. Clearly less attention is directed to surface chan...

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Veröffentlicht in:	Pharmaceutical research 2018-03, Vol.35 (3), p.69-11, Article 69
Hauptverfasser:	Aleandri, Simone, Schönenberger, Monica, Niederquell, Andres, Kuentz, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical methods Aprepitant Atomic force microscopy Bezafibrate Bezafibrate - chemistry Bezafibrate - pharmacokinetics Biochemistry Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedicine Cellulose Cellulose - analogs & derivatives Cellulose - chemistry Chemistry, Pharmaceutical Chromatography Dissolution Drug Compounding - methods Drug Liberation Drug Stability Drug Storage Drugs Excipients - chemistry Fenofibrate Fenofibrate - chemistry Fenofibrate - pharmacokinetics Gas chromatography Hydroxypropyl cellulose Hypolipidemic Agents - chemistry Hypolipidemic Agents - pharmacokinetics Inverse gas chromatography Medical Law Microscopy Microscopy, Atomic Force Nanoparticles Nanoparticles - chemistry Nanoparticles - ultrastructure Pharmaceuticals Pharmacology/Toxicology Pharmacy Research Paper Sodium Sodium dodecyl sulfate Sodium Dodecyl Sulfate - chemistry Sodium lauryl sulfate Solubility Sulfates Surface active agents Suspensions Temperature Wet milling
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