The path to metastatic mouse models of colorectal cancer

The study and comprehension of the molecular mechanisms underlying cancer biology strongly rely on mouse modeling. An ideal mouse model should have molecular, histopathological, and etiological characteristics as close as possible to those of the corresponding human tumors. Among solid tumors, color...

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Veröffentlicht in:	Oncogene 2018-05, Vol.37 (19), p.2481-2489
Hauptverfasser:	Romano, Gabriele, Chagani, Sharmeen, Kwong, Lawrence N.
Format:	Artikel
Sprache:	eng
Schlagworte:	42/41 42/70 631/67/1504/1885 631/67/70 64/60 Animal models Animals Apoptosis Carcinogens - toxicity Cell Biology Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - chemically induced Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Development and progression Disease Models, Animal Gene expression Genetic aspects Histochemistry Human Genetics Humans Internal Medicine Medicine Medicine & Public Health Metastases Metastasis Mice Molecular modelling Mutation Neoplasm Metastasis - genetics Neoplasm Metastasis - pathology Oncology Review Article Rodents Solid tumors Tumors
Online-Zugang:	Volltext
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