Altered Serotonin and Dopamine Metabolism in the CNS of Serotonin 5‐HT1A or 5‐HT1B Receptor Knockout Mice

: Measurements of serotonin (5‐HT), dopamine (DA), andnoradrenaline, and of 5‐HT and DA metabolites, were obtained by HPLC from 16brain regions and the spinal cord of 5‐HT1A or 5‐HT1Bknockout and wild‐type mice of the 129/Sv strain. In 5‐HT1Aknockouts, 5‐HT concentrations were unchanged throughout,...

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Veröffentlicht in:	Journal of neurochemistry 2000-12, Vol.75 (6), p.2415-2426
Hauptverfasser:	Ase, Ariel R., Reader, Tomás A., Hen, René, Riad, Mustapha, Descarries, Laurent
Format:	Artikel
Sprache:	eng
Schlagworte:	5‐HT1A knockout 5‐HT1B knockout Biological and medical sciences Brain and spinal cord Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Fundamental and applied biological sciences. Psychology Metabolites Monoamines Turnover Vertebrates: nervous system and sense organs
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