Beyond thrombosis: Anti-β2GPI domain 1 antibodies identify late pregnancy morbidity in anti-phospholipid syndrome

Antibodies against β2 glycoprotein I (anti-β2GPI) have been identified as the main pathogenic autoantibody subset in anti-phospholipid syndrome (APS); the most relevant epitope is a cryptic and conformation-dependent structure on β2GPI domain (D) 1. Anti-β2GPI domain profiling has been investigated...

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Veröffentlicht in:	Journal of autoimmunity 2018-06, Vol.90, p.76-83
Hauptverfasser:	Chighizola, Cecilia Beatrice, Pregnolato, Francesca, Andreoli, Laura, Bodio, Caterina, Cesana, Laura, Comerio, Chiara, Gerosa, Maria, Grossi, Claudia, Kumar, Rajesh, Lazzaroni, Maria Grazia, Mahler, Michael, Mattia, Elena, Nalli, Cecilia, Norman, Gary L., Raimondo, Maria Gabriella, Ruffatti, Amelia, Tonello, Marta, Trespidi, Laura, Tincani, Angela, Borghi, Maria Orietta, Meroni, Pier Luigi
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-phospholipid antibodies Anti-phospholipid syndrome Anti-β2GPI domain 1 antibodies Anti-β2GPI domain 4/5 antibodies Pregnancy morbidity
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