Evaluation of liquid biopsies for detection of emerging mutated genes in metastatic colorectal cancer

Detection of gene mutations is important for planning molecular targeted therapy. Although most gene mutations are concordant between primary colon cancers and their liver metastases, new mutations can emerge in metastases. The liquid biopsy is a newly developed, gene analytic method to detect mutat...

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Veröffentlicht in:	European journal of surgical oncology 2018-07, Vol.44 (7), p.975-982
Hauptverfasser:	Furuki, Hiroyasu, Yamada, Takeshi, Takahashi, Goro, Iwai, Takuma, Koizumi, Michihiro, Shinji, Seiichi, Yokoyama, Yasuyuki, Takeda, Kohki, Taniai, Nobuhiko, Uchida, Eiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Colon cancer Gene mutation Genomic evolution Liquid biopsy Next-generation sequencing
Online-Zugang:	Volltext
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