OAS1, 2, and 3: Significance During Active Tuberculosis?

OAS1, 2, and 3 are interferon-inducible antiviral proteins; however, their expression is prominent in blood transcriptomes of patients with tuberculosis. We propose that OAS expression enhances the type I IFN response and promotes disease progression during late-stage tuberculosis disease. Abstract...

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Veröffentlicht in:The Journal of infectious diseases 2018-04, Vol.217 (10), p.1517-1521
Hauptverfasser: Leisching, Gina, Wiid, Ian, Baker, Bienyameen
Format: Artikel
Sprache:eng
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