Method for estimation of toxic endotoxin in inactivated Salmonella vaccine in D-galactosamine-sensitized mice

We developed a method to estimate the content of the toxic endotoxin in inactivated Salmonella vaccine in D-galactosamine-sensitized mice. Ten-fold serially diluted vaccines were injected intraperitoneally into D-galactosamine-sensitized mice. Lethality in the mice was judged 3 days after the inject...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2004, Vol.66(12), pp.1591-1593
Hauptverfasser:	Takikawa, N. (Kitasato Inst., Tokyo (Japan)), Kawahara, K, Sawata, A, Kume, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacterial Vaccines - chemistry endotoxin ENDOTOXINS Endotoxins - analysis Galactosamine Lethal Dose 50 Limulus Limulus Test - methods METHODS MICE Mice - immunology Mice, Inbred C3H SALMONELLA vaccine VACCINES
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