Immunohistochemical analysis and prognostic significance of PD-L1, PD-1, and CD8+ tumor-infiltrating lymphocytes in Ewing’s sarcoma family of tumors (ESFT)

Ewing’s sarcoma family of tumors (ESFT) are aggressive neoplasms with scant tumor-infiltrating lymphocytes. We analyzed the immunohistochemical (IHC) expression of PD-L1 and PD-1 and their prognostic significance in clinically localized neoplasms in a cohort of 370 ESFT. Slides prepared from tissue...

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Veröffentlicht in:	Virchows Archiv : an international journal of pathology 2018-05, Vol.472 (5), p.815-824
Hauptverfasser:	Machado, Isidro, López-Guerrero, Jose Antonio, Scotlandi, Katia, Picci, Piero, Llombart-Bosch, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	CD8 antigen Correlation Ewings sarcoma Immunohistochemistry Lymphocytes Lymphocytes T Medical prognosis Medicine Medicine & Public Health Metastases Neoplasia Neoplasms Original Article Pathology PD-1 protein PD-L1 protein Prognosis Sarcoma Survival Tumor cells Tumor-infiltrating lymphocytes Tumors
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