SGLT2 Inhibitor-Associated Euglycemic Diabetic Ketoacidosis: A South Australian Clinical Case Series and Australian Spontaneous Adverse Event Notifications
Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been linked with diabetic ketoacidosis (DKA). However, characteristics of "at-risk" patients are less well described. Clinical cases were collected from South Australia between December 2015 and March 2017. Key issues identified were t...
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Veröffentlicht in: | Diabetes care 2018-04, Vol.41 (4), p.e47-e49 |
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creator | Meyer, Emily J Gabb, Genevieve Jesudason, David |
description | Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been linked with diabetic ketoacidosis (DKA). However, characteristics of "at-risk" patients are less well described. Clinical cases were collected from South Australia between December 2015 and March 2017. Key issues identified were that most patients did not recognize DKA, treating physicians often did not initially recognize DKA due to relative euglycemia, and effective treatment was delayed. |
doi_str_mv | 10.2337/dc17-1721 |
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Key issues identified were that most patients did not recognize DKA, treating physicians often did not initially recognize DKA due to relative euglycemia, and effective treatment was delayed.</description><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Glucose</subject><subject>Ketoacidosis</subject><subject>Medical personnel</subject><subject>Medical treatment</subject><subject>Patients</subject><subject>Physicians</subject><subject>Sodium</subject><issn>0149-5992</issn><issn>1935-5548</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNpdkc1O3DAUhS1UVAbogheoLHXTLtL6L3bMLpoOFHXULgbWkWPfFKOMPdgOEs_CyzajoVXV1T2L7x4d6UPogpLPjHP1xVmqKqoYPUILqnld1bVo3qAFoUJXtdbsBJ3m_EAIEaJp3qITpoUglLIFetlcr28Zvgn3vvclpqrNOVpvCji8mn6Nzxa23uKv3vRQ5vAdSjTWu5h9vsQt3sSp3ON2yiWZ0ZuAl6MP3poRL00GvIHkIWMT3L_MZhdDMQHilHHrniDN5OoJQsE_YvHD_F58DPkcHQ9mzPDu9Z6hu6vV7fJbtf55fbNs15UVVJRK9QOT0Mge1By1Nk7JflCEcdn3gx2EapwGIQZGbaOEM9AoYFxQqWVNjORn6OOhd5fi4wS5dFufLYzjYWLHCGGMEUnrGf3wH_oQpxTmdR2jhPCGcklm6tOBsinmnGDodslvTXruKOn2xrq9sW5vbGbfvzZO_RbcX_KPIv4b65CSDw</recordid><startdate>20180401</startdate><enddate>20180401</enddate><creator>Meyer, Emily J</creator><creator>Gabb, Genevieve</creator><creator>Jesudason, David</creator><general>American Diabetes Association</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-7450-5808</orcidid></search><sort><creationdate>20180401</creationdate><title>SGLT2 Inhibitor-Associated Euglycemic Diabetic Ketoacidosis: A South Australian Clinical Case Series and Australian Spontaneous Adverse Event Notifications</title><author>Meyer, Emily J ; Gabb, Genevieve ; Jesudason, David</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-7bf26e86be77bf99ad76bf70236bbfcf478d9e44f21c874dae87e234169650a63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Diabetes</topic><topic>Diabetes mellitus</topic><topic>Glucose</topic><topic>Ketoacidosis</topic><topic>Medical personnel</topic><topic>Medical treatment</topic><topic>Patients</topic><topic>Physicians</topic><topic>Sodium</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Meyer, Emily J</creatorcontrib><creatorcontrib>Gabb, Genevieve</creatorcontrib><creatorcontrib>Jesudason, David</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Diabetes care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Meyer, Emily J</au><au>Gabb, Genevieve</au><au>Jesudason, David</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>SGLT2 Inhibitor-Associated Euglycemic Diabetic Ketoacidosis: A South Australian Clinical Case Series and Australian Spontaneous Adverse Event Notifications</atitle><jtitle>Diabetes care</jtitle><addtitle>Diabetes Care</addtitle><date>2018-04-01</date><risdate>2018</risdate><volume>41</volume><issue>4</issue><spage>e47</spage><epage>e49</epage><pages>e47-e49</pages><issn>0149-5992</issn><eissn>1935-5548</eissn><abstract>Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been linked with diabetic ketoacidosis (DKA). 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language | eng |
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source | EZB Electronic Journals Library |
subjects | Diabetes Diabetes mellitus Glucose Ketoacidosis Medical personnel Medical treatment Patients Physicians Sodium |
title | SGLT2 Inhibitor-Associated Euglycemic Diabetic Ketoacidosis: A South Australian Clinical Case Series and Australian Spontaneous Adverse Event Notifications |
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