Effect of tiotropium on spontaneous expiratory flow–volume curves during exercise in GOLD 1-2 COPD

•Tiotropium decreased dynamic hyperinflation in COPD with SEFV curve concavity.•Areas-under-SEFV-curves compared in 20 COPD vs 16 age-matched untreated controls.•Tiotropium increased exercise RAR in GOLD 1-2 patients with SEFV curve concavity. This substudy of a large, randomized, controlled trial (...

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Veröffentlicht in:	Respiratory physiology & neurobiology 2018-05, Vol.251, p.8-15
Hauptverfasser:	Porszasz, Janos, Carraro, Nicolò, Cao, Robert, Gore, Ashwani, Ma, Shuyi, Jiang, Thomas, Maltais, François, Ferguson, Gary T., O’Donnell, Denis E., Shaikh, Asif, Rossiter, Harry B., Casaburi, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Constant work rate Dynamic hyperinflation Expiratory flow limitation Inspiratory capacity Rectangular area ratio Treadmill exercise
Online-Zugang:	Volltext
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