Gastric Carcinomas With Lymphoid Stroma: An Evaluation of the Histopathologic and Molecular Features

Gastric carcinoma with lymphoid stroma is an uncommon variant enriched for mutually exclusive Epstein-Barr virus (EBV) positivity and mismatch repair (MMR) deficiency. We performed this study to evaluate molecular alterations in this morphologically homogeneous subtype and compare them with 295 conv...

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Veröffentlicht in:	The American journal of surgical pathology 2018-04, Vol.42 (4), p.453-462
Hauptverfasser:	Hissong, Erika, Ramrattan, Girish, Zhang, Pan, Zhou, Xi Kathy, Young, Gloria, Klimstra, David S, Shia, Jinru, Fernandes, Helen, Yantiss, Rhonda K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor - analysis Biomarkers, Tumor - genetics Biopsy Carcinoma - chemistry Carcinoma - diagnosis Carcinoma - genetics Carcinoma - pathology DNA Mismatch Repair Female Genetic Predisposition to Disease Herpesvirus 4, Human - genetics High-Throughput Nucleotide Sequencing Humans Immunohistochemistry In Situ Hybridization Lymphocytes, Tumor-Infiltrating - chemistry Lymphocytes, Tumor-Infiltrating - pathology Male Microsatellite Instability Middle Aged Mutation Phenotype Retrospective Studies RNA, Viral - genetics Stomach Neoplasms - chemistry Stomach Neoplasms - diagnosis Stomach Neoplasms - genetics Stomach Neoplasms - pathology Stromal Cells - chemistry Stromal Cells - pathology
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