Transvenous Lead Extraction in Adults With Congenital Heart Disease: Insights From a 20-Year Single-Center Experience

Safety and feasibility data on transvenous lead extraction (TLE) in the challenging population of adults with congenital heart disease (A-CHD) are limited. Herein, we report the results of TLE in A-CHD during a 20-year period. All consecutive TLE procedures in A-CHD were included in a monocentric pr...

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Veröffentlicht in:Circulation. Arrhythmia and electrophysiology 2018-02, Vol.11 (2), p.e005409-e005409
Hauptverfasser: Gourraud, Jean-Baptiste, Chaix, Marie-A, Shohoudi, Azadeh, Pagé, Pierre, Dubuc, Marc, Thibault, Bernard, Poirier, Nancy C., Dore, Annie, Marcotte, François, Mongeon, François-Pierre, Asgar, Anita W., Ibrahim, Réda, Khairy, Paul, Mondésert, Blandine
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container_issue 2
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container_title Circulation. Arrhythmia and electrophysiology
container_volume 11
creator Gourraud, Jean-Baptiste
Chaix, Marie-A
Shohoudi, Azadeh
Pagé, Pierre
Dubuc, Marc
Thibault, Bernard
Poirier, Nancy C.
Dore, Annie
Marcotte, François
Mongeon, François-Pierre
Asgar, Anita W.
Ibrahim, Réda
Khairy, Paul
Mondésert, Blandine
description Safety and feasibility data on transvenous lead extraction (TLE) in the challenging population of adults with congenital heart disease (A-CHD) are limited. Herein, we report the results of TLE in A-CHD during a 20-year period. All consecutive TLE procedures in A-CHD were included in a monocentric prospective registry from 1996. A total of 121 leads were extracted in 49 A-CHD (median age, 38 years; 51% men) during 71 TLE procedures. Twenty-four (49%) patients had transposition of the great arteries. Main indications for extraction were infection in 34 (48%) and lead failure in 22 (31%). A laser sheath was required for 56 (46%) leads and a femoral approach for 10 (8%). Complete TLE was achieved for 111 leads (92%). In multivariable analysis, lead duration (odds ratio, 1.02; 95% confidence interval, 1.00-1.04;
doi_str_mv 10.1161/CIRCEP.117.005409
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Herein, we report the results of TLE in A-CHD during a 20-year period. All consecutive TLE procedures in A-CHD were included in a monocentric prospective registry from 1996. A total of 121 leads were extracted in 49 A-CHD (median age, 38 years; 51% men) during 71 TLE procedures. Twenty-four (49%) patients had transposition of the great arteries. Main indications for extraction were infection in 34 (48%) and lead failure in 22 (31%). A laser sheath was required for 56 (46%) leads and a femoral approach for 10 (8%). Complete TLE was achieved for 111 leads (92%). In multivariable analysis, lead duration (odds ratio, 1.02; 95% confidence interval, 1.00-1.04; &lt;0.01) and number of previous cardiac surgeries (odds ratio, 2.65; 95% confidence interval, 1.52-4.67; &lt;0.01) were predictive of TLE failure. No perioperative death or pericardial effusion was observed. Subpulmonary atrioventricular valve regurgitation increased in 8 patients (5 with transposition of the great arteries) and was independently associated with an implantable cardioverter defibrillator lead (odds ratio, 9.69; 95% confidence interval, 1.31-71.64; =0.03) and valvular vegetation (odds ratio, 7.29; 95% confidence interval, 1.32-40.51; =0.02). After a median of 54 (19-134) months of follow-up after the first TLE, 3 deaths occurred independently from lead management. Despite complex anatomic issues, TLE can be achieved successfully in most A-CHD using advanced extraction techniques. 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Arrhythmia and electrophysiology</title><addtitle>Circ Arrhythm Electrophysiol</addtitle><description>Safety and feasibility data on transvenous lead extraction (TLE) in the challenging population of adults with congenital heart disease (A-CHD) are limited. Herein, we report the results of TLE in A-CHD during a 20-year period. All consecutive TLE procedures in A-CHD were included in a monocentric prospective registry from 1996. A total of 121 leads were extracted in 49 A-CHD (median age, 38 years; 51% men) during 71 TLE procedures. Twenty-four (49%) patients had transposition of the great arteries. Main indications for extraction were infection in 34 (48%) and lead failure in 22 (31%). A laser sheath was required for 56 (46%) leads and a femoral approach for 10 (8%). Complete TLE was achieved for 111 leads (92%). In multivariable analysis, lead duration (odds ratio, 1.02; 95% confidence interval, 1.00-1.04; &lt;0.01) and number of previous cardiac surgeries (odds ratio, 2.65; 95% confidence interval, 1.52-4.67; &lt;0.01) were predictive of TLE failure. No perioperative death or pericardial effusion was observed. Subpulmonary atrioventricular valve regurgitation increased in 8 patients (5 with transposition of the great arteries) and was independently associated with an implantable cardioverter defibrillator lead (odds ratio, 9.69; 95% confidence interval, 1.31-71.64; =0.03) and valvular vegetation (odds ratio, 7.29; 95% confidence interval, 1.32-40.51; =0.02). After a median of 54 (19-134) months of follow-up after the first TLE, 3 deaths occurred independently from lead management. Despite complex anatomic issues, TLE can be achieved successfully in most A-CHD using advanced extraction techniques. 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Arrhythmia and electrophysiology</jtitle><addtitle>Circ Arrhythm Electrophysiol</addtitle><date>2018-02-01</date><risdate>2018</risdate><volume>11</volume><issue>2</issue><spage>e005409</spage><epage>e005409</epage><pages>e005409-e005409</pages><issn>1941-3149</issn><eissn>1941-3084</eissn><abstract>Safety and feasibility data on transvenous lead extraction (TLE) in the challenging population of adults with congenital heart disease (A-CHD) are limited. Herein, we report the results of TLE in A-CHD during a 20-year period. All consecutive TLE procedures in A-CHD were included in a monocentric prospective registry from 1996. A total of 121 leads were extracted in 49 A-CHD (median age, 38 years; 51% men) during 71 TLE procedures. Twenty-four (49%) patients had transposition of the great arteries. Main indications for extraction were infection in 34 (48%) and lead failure in 22 (31%). A laser sheath was required for 56 (46%) leads and a femoral approach for 10 (8%). Complete TLE was achieved for 111 leads (92%). In multivariable analysis, lead duration (odds ratio, 1.02; 95% confidence interval, 1.00-1.04; &lt;0.01) and number of previous cardiac surgeries (odds ratio, 2.65; 95% confidence interval, 1.52-4.67; &lt;0.01) were predictive of TLE failure. No perioperative death or pericardial effusion was observed. Subpulmonary atrioventricular valve regurgitation increased in 8 patients (5 with transposition of the great arteries) and was independently associated with an implantable cardioverter defibrillator lead (odds ratio, 9.69; 95% confidence interval, 1.31-71.64; =0.03) and valvular vegetation (odds ratio, 7.29; 95% confidence interval, 1.32-40.51; =0.02). After a median of 54 (19-134) months of follow-up after the first TLE, 3 deaths occurred independently from lead management. Despite complex anatomic issues, TLE can be achieved successfully in most A-CHD using advanced extraction techniques. Subpulmonary atrioventricular valve regurgitation is a prevalent complication, particularly in patients with transposition of the great arteries.</abstract><cop>United States</cop><pub>American Heart Association, Inc</pub><pmid>29437760</pmid><doi>10.1161/CIRCEP.117.005409</doi></addata></record>
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subjects Adult
Catheterization, Peripheral - methods
Defibrillators, Implantable - adverse effects
Device Removal - methods
Electrodes, Implanted - adverse effects
Equipment Failure
Feasibility Studies
Female
Femoral Vein
Follow-Up Studies
Forecasting
Heart Defects, Congenital - therapy
Humans
Incidence
Male
Middle Aged
Pacemaker, Artificial - adverse effects
Postoperative Complications - epidemiology
Prospective Studies
Quebec - epidemiology
Survival Rate - trends
title Transvenous Lead Extraction in Adults With Congenital Heart Disease: Insights From a 20-Year Single-Center Experience
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