Establishment of potent and specific synthetic substrate for dipeptidyl-peptidase 7

Bacterial dipeptidyl-peptidase (DPP) 7 liberates a dipeptide with a preference for aliphatic and aromatic penultimate residues from the N-terminus. Although synthetic substrates are useful for activity measurements, those currently used are problematic, because they are more efficiently degraded by...

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Veröffentlicht in:	Analytical biochemistry 2018-05, Vol.548, p.78-81
Hauptverfasser:	Nemoto, Takayuki K., Ono, Toshio, Ohara-Nemoto, Yuko
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - chemistry Dipeptidyl-peptidase 5 Dipeptidyl-peptidase 7 Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - chemistry Peptides - chemistry Periodontopathic bacteria Porphyromonas gingivalis Porphyromonas gingivalis - enzymology Substrate Specificity
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