Role of Brain Neuroinflammatory Factors on Hypertension in the Spontaneously Hypertensive Rat

•Neuroinflammatory events in SHR.•Elevated pro-inflammatory mRNA levels and hypertensive conditions.•Differing pro-inflammatory factors operating on cerebral-linked hypertension. It is already widely known that the different brain areas involved in blood pressure control, are highly vulnerable to th...

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Veröffentlicht in:	Neuroscience 2018-04, Vol.375, p.158-168
Hauptverfasser:	Avolio, Ennio, Pasqua, Teresa, Di Vito, Anna, Fazzari, Gilda, Cardillo, Gabriella, Alò, Raffaella, Cerra, Maria Carmela, Barni, Tullio, Angelone, Tommaso, Canonaco, Marcello
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - immunology Caspase 1 - metabolism Caspase 3 - metabolism hypertension Hypertension - immunology Inflammation - metabolism Interleukin-1beta - metabolism intracellular pathways Male Neuroimmunomodulation - physiology neuroinflammation NF-kappa B - metabolism Nitric Oxide Synthase Type II - metabolism NLR Family, Pyrin Domain-Containing 3 Protein - metabolism NLRP3 Rats, Inbred SHR Rats, Inbred WKY Vascular Endothelial Growth Factor A - metabolism
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