New insights on Parkinson's disease from differentiation of SH-SY5Y into dopaminergic neurons: An involvement of aquaporin4 and 9

The purpose of this research was to explore the behavior of aquaporins (AQPs) in an in vitro model of Parkinson's disease that is a recurrent neurodegenerative disorder caused by the gradual, progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Because of postmortem s...

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Veröffentlicht in:	Molecular and cellular neuroscience 2018-04, Vol.88, p.212-221
Hauptverfasser:	Avola, Rosanna, Graziano, Adriana Carol Eleonora, Pannuzzo, Giovanna, Albouchi, Ferdaous, Cardile, Venera
Format:	Artikel
Sprache:	eng
Schlagworte:	Aquaporin Aquaporin 4 - drug effects Aquaporin 4 - metabolism Aquaporins - drug effects Aquaporins - metabolism Cell Death - drug effects Cell Differentiation - drug effects Cell Line, Tumor Differentiation Dopaminergic neuron Dopaminergic Neurons - drug effects Dopaminergic Neurons - metabolism Humans Hydrogen Peroxide - pharmacology in vitro model Neurodegeneration Neuroprotective Agents - pharmacology Parkinson Disease - metabolism Parkinson's disease Tretinoin - pharmacology Tyrosine 3-Monooxygenase - drug effects Tyrosine 3-Monooxygenase - metabolism
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