Sensors for measuring subcellular zinc pools

Zinc homeostasis is essential for normal cellular function, and defects in this process are associated with a number of diseases including type 2 diabetes (T2D), neurological disorders and cardiovascular disease. Thus, variants in the SLC30A8 gene, encoding the vesicular/granular zinc transporter Zn...

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Veröffentlicht in:	Metallomics 2018-02, Vol.1 (2), p.229-239
Hauptverfasser:	Chabosseau, Pauline, Woodier, Jason, Cheung, Rebecca, Rutter, Guy A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biosensing Techniques Cardiovascular diseases Cation Transport Proteins - metabolism Cytosol Cytosol - metabolism Diabetes mellitus Diabetes mellitus (non-insulin dependent) Endoplasmic reticulum Endoplasmic Reticulum - metabolism Golgi apparatus Golgi Apparatus - metabolism Homeostasis Humans Hypertension Insulin Mitochondria Neurological diseases Secretory vesicles Secretory Vesicles - metabolism Sensors Subcellular Fractions Zinc Zinc - analysis Zinc transporter
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