A possible regulatory role of 17 beta -estradiol and tamoxifen on glyoxalase I andglyoxalase II genes expression in MCF7 and BT20 human breast cancer cells

The glutathione-dependent glyoxalases system, composed of glyoxalase I (GloI) and glyoxalase II (GloII) enzymes, is involved in the detoxification of methylglyoxal, a by-product of cell metabolism. Aberrations in the expression of glyoxalase genes in several human cancers have been reported. Sometim...

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Veröffentlicht in:Breast cancer research and treatment 2006-03, Vol.96 (2), p.187-196
Hauptverfasser: Rulli, Antonio, Antognelli, Cinzia, Prezzi, Eleonora, Baldracchini, Francesca, Piva, Francesco, Giovannini, Elvio, Talesa, Vincenzo
Format: Artikel
Sprache:eng
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