ABVD plus radiotherapy versus EVE plus radiotherapy in unfavorable stage IA and IIA Hodgkin's lymphoma: results from an Intergruppo Italiano Linfomi randomized study

Background: In 1997, the Intergruppo Italiano Linfomi started a randomized trial to evaluate, in unfavorable stage IA and IIA Hodgkin's lymphoma (HL) patients, the efficacy and toxicity of the low toxic epirubicin, vinblastine and etoposide (EVE) regimen followed by involved field radiotherapy...

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Veröffentlicht in:	Annals of oncology 2008-04, Vol.19 (4), p.763-768
Hauptverfasser:	Pavone, V., Ricardi, U., Luminari, S., Gobbi, P., Federico, M., Baldini, L., Iannitto, E., Ucci, G., Marcheselli, L., Orsucci, L., Angelucci, E., Liberati, M., Gavarotti, P., Levis, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	ABVD-EVE Adult Aged Anemia - chemically induced Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Bleomycin - administration & dosage Bleomycin - adverse effects Chemotherapy, Adjuvant Dacarbazine - administration & dosage Dacarbazine - adverse effects Disease-Free Survival Doxorubicin - administration & dosage Doxorubicin - adverse effects early stage unfavorable Hodgkin lymphoma Epirubicin - administration & dosage Epirubicin - adverse effects Etoposide - administration & dosage Etoposide - adverse effects Female Heart Diseases - chemically induced Hematologic and hematopoietic diseases Hodgkin Disease - drug therapy Hodgkin Disease - pathology Hodgkin Disease - radiotherapy Humans Infections - etiology Italy Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Leukopenia - chemically induced Male Medical sciences Middle Aged Neoplasm Staging Pharmacology. Drug treatments radiotherapy Radiotherapy, Adjuvant Severity of Illness Index Treatment Outcome Vinblastine - administration & dosage Vinblastine - adverse effects
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