Successful Treatment of Disseminated Cutaneous Leishmaniasis With Liposomal Amphotericin B and Miltefosine in an Eight-year-old Girl
This case report presents an 8-year-old girl, from Fars province in Iran, diagnosed with cutaneous leishmaniasis in the form of multiple nodular, ulcerative and crusted lesions disseminated on the face, trunk and extremities. The result of direct smear of ulcers was positive for Leishmania parasite....
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| Veröffentlicht in: | The Pediatric infectious disease journal 2018-03, Vol.37 (3), p.275-277 |
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| container_end_page | 277 |
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| container_issue | 3 |
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| container_title | The Pediatric infectious disease journal |
| container_volume | 37 |
| creator | Hamzavi, Seyedeh Sedigheh Sanaei Dashti, Anahita Kadivar, Mohammad Rahim Pouladfar, Gholamreza Pourabbas, Bahman |
| description | This case report presents an 8-year-old girl, from Fars province in Iran, diagnosed with cutaneous leishmaniasis in the form of multiple nodular, ulcerative and crusted lesions disseminated on the face, trunk and extremities. The result of direct smear of ulcers was positive for Leishmania parasite. The patient had no immunodeficiency or relevant family history making her susceptible for disseminated cutaneous leishmaniasis. The skin lesions failed to respond to multiple treatment courses of meglumine antimoniate or amphotericin B but were successfully treated with simultaneous miltefosine and liposomal amphotericin B. |
| doi_str_mv | 10.1097/INF.0000000000001741 |
| format | Article |
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| ispartof | The Pediatric infectious disease journal, 2018-03, Vol.37 (3), p.275-277 |
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| language | eng |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Amphotericin B - administration & dosage Amphotericin B - therapeutic use Antiprotozoal Agents - administration & dosage Antiprotozoal Agents - therapeutic use Child Female Humans Iran Leishmaniasis, Cutaneous - diagnosis Leishmaniasis, Cutaneous - drug therapy Leishmaniasis, Cutaneous - parasitology Phosphorylcholine - administration & dosage Phosphorylcholine - analogs & derivatives Phosphorylcholine - therapeutic use Skin - pathology Treatment Outcome |
| title | Successful Treatment of Disseminated Cutaneous Leishmaniasis With Liposomal Amphotericin B and Miltefosine in an Eight-year-old Girl |
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