Epidermal lipid composition, barrier integrity, and eczematous inflammation are associated with skin microbiome configuration

Genomic approaches have revealed characteristic site specificities of skin bacterial community structures. In addition, in children with atopic dermatitis (AD), characteristic shifts were described at creases and, in particular, during flares, which have been postulated to mirror disturbed skin barr...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2018-05, Vol.141 (5), p.1668-1676.e16
Hauptverfasser:	Baurecht, Hansjörg, Rühlemann, Malte C., Rodríguez, Elke, Thielking, Frederieke, Harder, Inken, Erkens, Anna-Sophie, Stölzl, Dora, Ellinghaus, Eva, Hotze, Melanie, Lieb, Wolfgang, Wang, Sheng, Heinsen-Groth, Femke-Anouska, Franke, Andre, Weidinger, Stephan
Format:	Artikel
Sprache:	eng
Schlagworte:	Abundance Actinobacteria Atopic dermatitis Bacteria Children Chryseobacterium Community structure Deoxyribonucleic acid Dermatitis DNA Eczema Fatty acids Filaggrin Firmicutes Lesions Lipid composition lipidome Lipids microbiome Microbiomes Mutation Physiology rRNA 16S Skin Skin diseases Species diversity Staphylococcus Taxonomy
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