The role of type I interferons in innate and adaptive immunity against viruses in Atlantic salmon

Type I IFNs (IFN-I) are cytokines, which play a crucial role in innate and adaptive immunity against viruses of vertebrates. In essence, IFN-I are induced and secreted upon host cell recognition of viral nucleic acids and protect other cells against infection by inducing antiviral proteins. Atlantic...

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Veröffentlicht in:	Developmental and comparative immunology 2018-03, Vol.80, p.41-52
1. Verfasser:	Robertsen, Børre
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive Immunity Adjuvant adjuvants Anemia Animals Antiviral activity antiviral properties antiviral proteins Cell recognition Coding Cytokines Deoxyribonucleic acid disease control DNA DNA vaccine DNA vaccines Fish Fish Diseases - immunology Fish Proteins - metabolism Genes IFN Immunity Immunity, Innate Infections Injection Interferon interferon regulatory factors Interferon Type I - metabolism interferons intramuscular injection ISG mammals Nucleic acids Orthomyxoviridae Infections - immunology Plasmids Prophylaxis Proteins Receptors recombinant vaccines Salmo salar Salmo salar - immunology Salmon Salmon isavirus Studies TLR Vertebrates Viruses
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