A Gold@Polydopamine Core–Shell Nanoprobe for Long-Term Intracellular Detection of MicroRNAs in Differentiating Stem Cells

The capability of monitoring the differentiation process in living stem cells is crucial to the understanding of stem cell biology and the practical application of stem-cell-based therapies, yet conventional methods for the analysis of biomarkers related to differentiation require a large number of...

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Veröffentlicht in:	Journal of the American Chemical Society 2015-06, Vol.137 (23), p.7337-7346
Hauptverfasser:	Choi, Chun Kit K, Li, Jinming, Wei, Kongchang, Xu, Yang J, Ho, Lok Wai C, Zhu, Meiling, To, Kenneth K. W, Choi, Chung Hang J, Bian, Liming
Format:	Artikel
Sprache:	eng
Schlagworte:	bone formation cell culture Cell Differentiation culture media dissociation DNA drugs fibroblasts fluorescence gold Gold - chemistry Humans Indoles - chemistry Intracellular Space - chemistry Mesenchymal Stromal Cells - chemistry Mesenchymal Stromal Cells - cytology microRNA MicroRNAs - analysis Molecular Probes - chemistry Molecular Structure monitoring nanogold Nanoparticles - chemistry osteoblasts Polymers - chemistry screening stem cells transfection
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