Tying up the Ends: Plasticity in the Recognition of Single-Stranded DNA at Telomeres

Telomeres terminate nearly exclusively in single-stranded DNA (ssDNA) overhangs comprised of the G-rich 3′ end. This overhang varies widely in length from species to species, ranging from just a few bases to several hundred nucleotides. These overhangs are not merely a remnant of DNA replication but...

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Veröffentlicht in:	Biochemistry (Easton) 2016-09, Vol.55 (38), p.5326-5340
Hauptverfasser:	Lloyd, Neil R, Dickey, Thayne H, Hom, Robert A, Wuttke, Deborah S
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA damage DNA replication DNA, Single-Stranded - chemistry humans mutation nucleotides proteins Schizosaccharomyces - chemistry Schizosaccharomyces pombe Schizosaccharomyces pombe Proteins - chemistry single-stranded DNA telomerase Telomere telomeres yeasts
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