Low Dietary c9t11-Conjugated Linoleic Acid Intake from Dairy Fat or Supplements Reduces Inflammation in Collagen-Induced Arthritis

Dietary cis -9, trans -11 (c9t11) conjugated linoleic acid (CLA) fed at 0.5 % w/w was previously shown to attenuate inflammation in the murine collagen-induced (CA) arthritis model, and growing evidence implicates c9t11-CLA as a major anti-inflammatory component of dairy fat. To understand c9t11-CLA...

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Veröffentlicht in:	Lipids 2016-07, Vol.51 (7), p.807-819
Hauptverfasser:	Huebner, Shane M., Olson, Jake M., Campbell, James P., Bishop, Jeffrey W., Crump, Peter M., Cook, Mark E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals anti-inflammatory activity Anti-Inflammatory Agents - administration & dosage Anti-Inflammatory Agents - pharmacology arthritis Arthritis, Experimental - diet therapy Arthritis, Experimental - immunology Biomedical and Life Sciences Butter Collagen‐induced arthritis Conjugated linoleic acid corn oil Dairy fat dietary fat Dietary Fats - analysis Dietary Supplements - analysis Dose-Response Relationship, Drug Inflammation interleukin-1beta Interleukin-1beta - blood interleukin-6 Interleukin-6 - blood Life Sciences Linoleic Acids, Conjugated - administration & dosage Linoleic Acids, Conjugated - pharmacology Lipidology Medical Biochemistry Medicinal Chemistry Mice Microbial Genetics and Genomics Neurochemistry Nutrition Oils & fats Original Article Treatment Outcome tumor necrosis factor-alpha Tumor Necrosis Factor-alpha - blood
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