Effects of MiR‐137 genetic risk score on brain volume and cortical measures in patients with schizophrenia and controls

Multiple genome‐wide association studies of schizophrenia have implicated genetic variants within the gene encoding microRNA‐137. As risk variants within or regulated by MIR137 have been implicated in memory performance, we investigated the additive effects of schizophrenia‐associated risk variants...

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Veröffentlicht in:	American journal of medical genetics. Part B, Neuropsychiatric genetics Neuropsychiatric genetics, 2018-04, Vol.177 (3), p.369-376
Hauptverfasser:	Cosgrove, Donna, Mothersill, David O., Whitton, Laura, Harold, Denise, Kelly, Sinead, Holleran, Laurena, Holland, Jessica, Anney, Richard, Richards, Alex, Mantripragada, Kiran, Owen, Michael, O'Donovan, Michael C., Gill, Michael, Corvin, Aiden, Morris, Derek W., Donohoe, Gary
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Brain - metabolism Brain - pathology Cortex Female Genetic diversity Genetic Predisposition to Disease Genetics Genome-wide association studies Genome-Wide Association Study Genomes GWAS Hippocampus Humans Male Mental disorders MicroRNAs - genetics miRNA Multifactorial Inheritance Neuropsychological Tests polygene Polymorphism, Single Nucleotide Psychosis Psychotic Disorders - genetics Psychotic Disorders - metabolism Psychotic Disorders - pathology Risk Factors Schizophrenia Schizophrenia - genetics Schizophrenia - metabolism Schizophrenia - pathology Surface area total brain volume
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