Oleamide suppresses inflammatory responses in LPS-induced RAW264.7 murine macrophages and alleviates paw edema in a carrageenan-induced inflammatory rat model

Oleamide compounds purified from green algae have been used for the prevention and treatment of atherosclerosis, thrombosis, arthritis, and cancer. They function through their metabolic conversion into prostaglandins, thromboxanes, and leukotrienes. However, the actual mechanism of action has not be...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International immunopharmacology 2018-03, Vol.56, p.179-185
Hauptverfasser:	Moon, Sung-Min, Lee, Seul Ah, Hong, Joon Ho, Kim, Jae-Sung, Kim, Do Kyung, Kim, Chun Sung
Format:	Artikel
Sprache:	eng
Schlagworte:	Algae Animals Anti-inflammatory agents Anti-Inflammatory Agents - pharmacology Arteriosclerosis Arthritis Atherosclerosis Body weight Cancer Carrageenan Codium fragile COX-2 Cyclooxygenase 2 - genetics Cyclooxygenase 2 - metabolism Cyclooxygenase-2 Cytokines Cytokines - metabolism Dinoprostone - metabolism Edema Edema - drug therapy Extracellular signal-regulated kinase Gene expression Humans Inflammation Mediators - metabolism Inflammatory diseases iNOS Interleukin 6 Kinases Leukotrienes Lipopolysaccharides Lipopolysaccharides - immunology Macrophages Macrophages - physiology MAP Kinase Signaling System MAPKs Medical treatment Mice mRNA NF-kappa B - metabolism NF-κB NF-κB protein Nitric Oxide Synthase Type II - genetics Nitric Oxide Synthase Type II - metabolism Nitric-oxide synthase Nitrites - metabolism Nuclear transport Oleamide Oleic Acids - pharmacology Phosphorylation Prostaglandin E2 Prostaglandins Protein expression Protein Transport Proteins Rats RAW 264.7 Cells RAW264.7 murine macrophages Thromboembolism Thrombosis Translocation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!