Characterization of medroxyprogesterone and DMBA-induced multilineage mammary tumors by gene expression profiling

Mouse mammary tumors arising during medroxyprogesterone‐DMBA‐mediated mammary carcinogenesis comprised three distinct phenotypes: adenocarcinoma, squamous cell carcinoma, and myoepithelial carcinoma. The molecular signature for each of the three tumor subsets was characterized by gene microarray ana...

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Veröffentlicht in:	Molecular carcinogenesis 2005-09, Vol.44 (1), p.42-50
Hauptverfasser:	Yin, Yuzhi, Bai, Renkui, Russell, Robert G., Beildeck, Marcy E., Xie, Zhihui, Kopelovich, Levy, Glazer, Robert I.
Format:	Artikel
Sprache:	eng
Schlagworte:	9,10-Dimethyl-1,2-benzanthracene - pharmacology adenocarcinoma adenosquamous Animals carcinogenesis DMBA Female Gene Expression Profiling Gene Expression Regulation, Neoplastic - drug effects Gene Expression Regulation, Neoplastic - genetics gene microarray Immunohistochemistry mammary Mammary Neoplasms, Experimental - chemically induced Mammary Neoplasms, Experimental - classification Mammary Neoplasms, Experimental - genetics Mammary Neoplasms, Experimental - metabolism medroxyprogesterone Medroxyprogesterone - pharmacology Mice myoepithelial RNA, Messenger - genetics RNA, Messenger - metabolism squamous
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